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Slco4a1 Gene Detail
Summary
  • Symbol
    Slco4a1
  • Name
    solute carrier organic anion transporter family, member 4a1
  • Synonyms
    MGC:28799, MGC:28824, OATP-E, Slc21a12
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351866
    NCBI Gene: 108115
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:180098038-180116660 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 102.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    508 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351866
 protein coding gene Chr2:180098019-180116660 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026994
 protein coding gene Chr2:186974655-186993986 (+)
A/J MGP_AJ_G0026960
 protein coding gene Chr2:179298358-179317072 (+)
AKR/J MGP_AKRJ_G0026930
 protein coding gene Chr2:184675018-184693778 (+)
BALB/cJ MGP_BALBcJ_G0026969
 protein coding gene Chr2:179760719-179779393 (+)
C3H/HeJ MGP_C3HHeJ_G0026710
 protein coding gene Chr2:185009989-185029377 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027415
 protein coding gene Chr2:192372564-192393094 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024780
 protein coding gene Chr2:169990428-170009336 (+)
CAST/EiJ MGP_CASTEiJ_G0026169
 protein coding gene Chr2:183260196-183278862 (+)
CBA/J MGP_CBAJ_G0026687
 protein coding gene Chr2:199368030-199389518 (+)
DBA/2J MGP_DBA2J_G0026825
 protein coding gene Chr2:178395330-178414049 (+)
FVB/NJ MGP_FVBNJ_G0026791
 protein coding gene Chr2:177004769-177023883 (+)
LP/J MGP_LPJ_G0026926
 protein coding gene Chr2:186978821-186997519 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026810
 protein coding gene Chr2:201974185-201993855 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027474
 protein coding gene Chr2:184627970-184646665 (+)
PWK/PhJ MGP_PWKPhJ_G0025905
 protein coding gene Chr2:175905505-175924258 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025705
 protein coding gene Chr2:181122777-181141488 (+)
WSB/EiJ MGP_WSBEiJ_G0026241
 protein coding gene Chr2:185608259-185626952 (+)



Homology
more
  • Human Ortholog
    SLCO4A1, solute carrier organic anion transporter family member 4A1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLCO4A1, solute carrier organic anion transporter family member 4A1
  • Synonyms
    OATP1, OATP4A1, OATP-E, OATPE, OATPRP1, POAT, SLC21A12
  • Links
    NCBI Gene ID: 28231
    neXtProt AC: NX_Q96BD0
    UniProt: Q96BD0

  • Chr Location
    20q13.33; chr20:62642503-62690740 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    818
  • Tissues
    104
  • cDNA Data
    29
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038963 Ensembl Gene Model | MGI Sequence Detail 18623 C57BL/6J ±  kb
transcript ENSMUST00000038259 Ensembl | MGI Sequence Detail 3010 Not Applicable  
polypeptide ENSMUSP00000046502 Ensembl | MGI Sequence Detail 723 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 32
    cDNA 30
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 38
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:93300 Blackshaw S, et al., Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
  • Latest
    J:227211 Zhang Y, et al., Maternal bile acid transporter deficiency promotes neonatal demise. Nat Commun. 2015;6:8186
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory