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Fbxo17 Gene Detail
Summary
  • Symbol
    Fbxo17
  • Name
    F-box protein 17
  • Synonyms
    Fbg4, Fbx17, FBXO26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354707
    NCBI Gene: 50760
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:28416229-28437569 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.90 cM, cytoband A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    857 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354707
protein coding gene Chr7:28416176-28437570 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031955
protein coding gene Chr7:27537372-27566351 (+)
A/J MGP_AJ_G0031933
protein coding gene Chr7:26860846-26884678 (+)
AKR/J MGP_AKRJ_G0031865
protein coding gene Chr7:27552499-27574810 (+)
BALB/cJ MGP_BALBcJ_G0031940
protein coding gene Chr7:27020936-27044037 (+)
C3H/HeJ MGP_C3HHeJ_G0031659
protein coding gene Chr7:27929700-27953022 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032404
protein coding gene Chr7:28426848-28469929 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029456
protein coding gene Chr7:27916880-27943692 (+)
CAST/EiJ MGP_CASTEiJ_G0030994
protein coding gene Chr7:21243372-21272333 (+)
CBA/J MGP_CBAJ_G0031625
protein coding gene Chr7:29715426-29738748 (+)
DBA/2J MGP_DBA2J_G0031777
protein coding gene Chr7:26615165-26637280 (+)
FVB/NJ MGP_FVBNJ_G0031734
protein coding gene Chr7:26692526-26713715 (+)
LP/J MGP_LPJ_G0031857
protein coding gene Chr7:27871218-27896114 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031770
protein coding gene Chr7:29182077-29205300 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032434
protein coding gene Chr7:27028516-27054088 (+)
PWK/PhJ MGP_PWKPhJ_G0030719
protein coding gene Chr7:21640563-21661788 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030552
protein coding gene Chr7:18053415-18074887 (+)
WSB/EiJ MGP_WSBEiJ_G0031103
protein coding gene Chr7:27395798-27422459 (+)



Homology
more
  • Human Ortholog
    FBXO17, F-box protein 17
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO17, F-box protein 17
  • Synonyms
    FBG4, Fbx17, FBX26, FBXO26
  • Links
    NCBI Gene ID: 115290
    neXtProt AC: NX_Q96EF6
    UniProt: Q96EF6

  • Chr Location
    19q13.2; chr19:38941401-38975742 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030598 Ensembl Gene Model | MGI Sequence Detail 21341 C57BL/6J ±  kb
transcript ENSMUST00000108278 Ensembl | MGI Sequence Detail 1806 Not Applicable  
polypeptide ENSMUSP00000103913 Ensembl | MGI Sequence Detail 286 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
  • Latest
    J:255082 Kurogi S, et al., Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models. Sci Rep. 2017 Jan 20;7:40692

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory