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Atp11a Gene Detail
Summary
  • Symbol
    Atp11a
  • Name
    ATPase, class VI, type 11A
  • Synonyms
    4930558F19Rik, 9130422H11Rik, Ih, LOC100045280
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354735
    NCBI Gene: 50770
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:12807016-12918728 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 5.73 cM, cytoband A2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2532 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354735
 protein coding gene Chr8:12807014-12918728 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033366
 protein coding gene Chr8:10062688-10174420 (+)
A/J MGP_AJ_G0033346
 protein coding gene Chr8:9701025-9813069 (+)
AKR/J MGP_AKRJ_G0033277
 protein coding gene Chr8:9966129-10077105 (+)
BALB/cJ MGP_BALBcJ_G0033347
 protein coding gene Chr8:9838436-9953342 (+)
C3H/HeJ MGP_C3HHeJ_G0033060
 protein coding gene Chr8:10175817-10286659 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033859
 protein coding gene Chr8:10434014-10545733 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030828
 protein coding gene Chr8:9204589-9319367 (+)
CAST/EiJ MGP_CASTEiJ_G0032382
 protein coding gene Chr8:9932380-10053773 (+)
CBA/J MGP_CBAJ_G0033033
 protein coding gene Chr8:10874029-10990332 (+)
DBA/2J MGP_DBA2J_G0033186
 protein coding gene Chr8:9662668-9773433 (+)
FVB/NJ MGP_FVBNJ_G0033135
 protein coding gene Chr8:9661122-9773448 (+)
LP/J MGP_LPJ_G0033280
 protein coding gene Chr8:9985145-10098042 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033169
 protein coding gene Chr8:11133885-11249982 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033876
 protein coding gene Chr8:10022583-10137946 (+)
PWK/PhJ MGP_PWKPhJ_G0032095
 protein coding gene Chr8:9696291-9815292 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031937
 protein coding gene Chr8:9913169-10026806 (+)
WSB/EiJ MGP_WSBEiJ_G0032498
 protein coding gene Chr8:10057202-10171309 (+)



Homology
more
  • Human Ortholog
    ATP11A, ATPase phospholipid transporting 11A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP11A, ATPase phospholipid transporting 11A
  • Synonyms
    ATPIH, ATPIS, AUNA2, DFNA84, HLD24
  • Links
    NCBI Gene ID: 23250
    neXtProt AC: NX_P98196
    UniProt: P98196

  • Chr Location
    13q34; chr13:112690038-112887168 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human ATP11A associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    50 phenotypes from 2 alleles in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a conditional allele activated in muscle cells exhibit abnormal myoblast function in culture and abnormal skeletal muscle regeneration.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    971
  • Tissues
    76
  • cDNA Data
    24
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 50770 NCBI Gene Model | MGI Sequence Detail 111713 C57BL/6J ±  kb
    transcript NR_121603 RefSeq | MGI Sequence Detail 7648 C57BL/6  
    polypeptide P98197 UniProt | EBI | MGI Sequence Detail 1187 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 26
      Primer pair 3

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1922594, MGI:2146150
    References
    more
    • Summaries
      All 62
      Developmental Gene Expression 7
      Gene Ontology 11
      Phenotypes 18
    • Earliest
      J:59384 Halleck MS, et al., Differential expression of putative transbilayer amphipath transporters. Physiol Genomics. 1999 Nov 11;1(3):139-50
    • Latest
      J:350444 Martinez-Mayer J, et al., Knockout mice with pituitary malformations help identify human cases of hypopituitarism. Genome Med. 2024 May 31;16(1):75
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory