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Krtap5-4 Gene Detail
Summary
  • Symbol
    Krtap5-4
  • Name
    keratin associated protein 5-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1354758
    NCBI Gene: 50775
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141857239-141858240 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 87.87 cM, cytoband F5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    142 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1354758
 protein coding gene Chr7:141857239-141858331 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033252
 protein coding gene Chr7:147543931-147544932 (+)
A/J MGP_AJ_G0033235
 protein coding gene Chr7:143292901-143293876 (+)
AKR/J MGP_AKRJ_G0033167
 protein coding gene Chr7:147310054-147313630 (+)
BALB/cJ MGP_BALBcJ_G0033236
 protein coding gene Chr7:143055073-143056070 (+)
C3H/HeJ MGP_C3HHeJ_G0032951
 protein coding gene Chr7:147068337-147069242 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033746
 protein coding gene Chr7:152898787-152900612 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030718
 protein coding gene Chr7:144499296-144500375 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0032922
 protein coding gene Chr7:158128063-158129094 (+)
DBA/2J MGP_DBA2J_G0033076
 protein coding gene Chr7:141245623-141246564 (+)
FVB/NJ MGP_FVBNJ_G0033025
 protein coding gene Chr7:141178898-141179899 (+)
LP/J MGP_LPJ_G0033169
 protein coding gene Chr7:149059178-149060149 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033059
 protein coding gene Chr7:158755658-158756702 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033765
 protein coding gene Chr7:146256037-146257068 (+)
PWK/PhJ MGP_PWKPhJ_G0031981
 protein coding gene Chr7:134564904-134566015 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031828
 protein coding gene Chr7:133056932-133057796 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRTAP5-10, keratin associated protein 5-10
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP5-10, keratin associated protein 5-10
  • Synonyms
    KRTAP5.10
  • Links
    NCBI Gene ID: 387273
    neXtProt AC: NX_Q6L8G5
    UniProt: Q6L8G5

  • Chr Location
    11q13.4; chr11:71565563-71566735 (+)  GRCh38
  • Human Ortholog
    KRTAP5-11, keratin associated protein 5-11
  • Synonyms
    KRTAP5.11, KRTAP5-5, KRTAP5-6
  • Links
    NCBI Gene ID: 440051
    neXtProt AC: NX_Q6L8G4
    UniProt: Q6L8G4

  • Chr Location
    11q13.4; chr11:71581855-71603353 (-)  GRCh38
  • Human Ortholog
    KRTAP5-2, keratin associated protein 5-2
  • Synonyms
    KRTAP5.2, KRTAP5-8
  • Links
    NCBI Gene ID: 440021
    neXtProt AC: NX_Q701N4
    UniProt: Q701N4

  • Chr Location
    11p15.5; chr11:1597177-1598294 (-)  GRCh38
  • Human Ortholog
    KRTAP5-3, keratin associated protein 5-3
  • Synonyms
    KRTAP5.3, KRTAP5-9
  • Links
    NCBI Gene ID: 387266
    neXtProt AC: NX_Q6L8H2
    UniProt: Q6L8H2

  • Chr Location
    11p15.5; chr11:1607565-1608463 (-)  GRCh38
  • Human Ortholog
    KRTAP5-7, keratin associated protein 5-7
  • Synonyms
    KRTAP5-3, KRTAP5.7
  • Links
    NCBI Gene ID: 440050
    neXtProt AC: NX_Q6L8G8
    UniProt: Q6L8G8

  • Chr Location
    11q13.4; chr11:71527267-71528669 (+)  GRCh38
  • Human Ortholog
    KRTAP5-9, keratin associated protein 5-9
  • Synonyms
    KRN1, KRTAP5-1, KRTAP5.9
  • Links
    NCBI Gene ID: 3846
    neXtProt AC: NX_P26371
    UniProt: P26371

  • Chr Location
    11q13.4; chr11:71548420-71549608 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Genomic Mutations
    1 involving Krtap5-4
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    1
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 50775 NCBI Gene Model | MGI Sequence Detail 1002 C57BL/6J ±  kb
transcript NM_015809 RefSeq | MGI Sequence Detail 1002 C57BL/6  
polypeptide Q62220 UniProt | EBI | MGI Sequence Detail 223 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
Molecular
Reagents
less
  • All nucleic 7
    Genomic 3
    cDNA 3
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:19083 Wood L, et al., Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle [published erratum appears in J Biol Chem 1991 Feb 25;266(6):4024]. J Biol Chem. 1990 Dec 5;265(34):21375-80
  • Latest
    J:150086 Kiso M, et al., The disruption of Sox21-mediated hair shaft cuticle differentiation causes cyclic alopecia in mice. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9292-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory