About   Help   FAQ
Ccnc Gene Detail
Summary
  • Symbol
    Ccnc
  • Name
    cyclin C
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858199
    NCBI Gene: 51813
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:21727705-21759917 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 8.86 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    960 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858199
 protein coding gene Chr4:21727701-21759922 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028090
 protein coding gene Chr4:18745369-18780069 (+)
A/J MGP_AJ_G0028048
 protein coding gene Chr4:18186233-18217943 (+)
AKR/J MGP_AKRJ_G0028013
 protein coding gene Chr4:18591429-18623001 (+)
BALB/cJ MGP_BALBcJ_G0028059
 protein coding gene Chr4:18244190-18277794 (+)
C3H/HeJ MGP_C3HHeJ_G0027789
 protein coding gene Chr4:18773122-18806856 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028502
 protein coding gene Chr4:19507121-19542009 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025844
 protein coding gene Chr4:16846961-16878271 (+)
CAST/EiJ MGP_CASTEiJ_G0027244
 protein coding gene Chr4:18531906-18570229 (+)
CBA/J MGP_CBAJ_G0027762
 protein coding gene Chr4:20067644-20104423 (+)
DBA/2J MGP_DBA2J_G0027905
 protein coding gene Chr4:18053475-18088497 (+)
FVB/NJ MGP_FVBNJ_G0027871
 protein coding gene Chr4:17768455-17801017 (+)
LP/J MGP_LPJ_G0028014
 protein coding gene Chr4:18819163-18852601 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027904
 protein coding gene Chr4:21287915-21335242 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028561
 protein coding gene Chr4:18544885-18580221 (+)
PWK/PhJ MGP_PWKPhJ_G0026964
 protein coding gene Chr4:17882811-17915809 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026793
 protein coding gene Chr4:18378424-18413018 (+)
WSB/EiJ MGP_WSBEiJ_G0027321
 protein coding gene Chr4:18553912-18589594 (+)



Homology
more
  • Human Ortholog
    CCNC, cyclin C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCNC, cyclin C
  • Synonyms
    CycC, hSRB11, SRB11
  • Links
    NCBI Gene ID: 892
    neXtProt AC: NX_P24863
    UniProt: P24863

  • Chr Location
    6q16.2; chr6:99542387-99568825 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 1 genetic background
    1 phenotype from multigenic genotypes
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice die prenatally and exhibit growth retardation and placental defects.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    801
  • Tissues
    36
  • cDNA Data
    55
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 51813 NCBI Gene Model | MGI Sequence Detail 32213 C57BL/6J ±  kb
transcript NM_001290422 RefSeq | MGI Sequence Detail 3480 C57BL/6  
polypeptide Q62447 UniProt | EBI | MGI Sequence Detail 283 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 58
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2140293, MGI:2140460
References
more
  • Summaries
    All 60
    Developmental Gene Expression 10
    Gene Ontology 7
    Phenotypes 18
  • Earliest
    J:57122 Kohn KW, Molecular interaction map of the mammalian cell cycle control and DNA repair systems. Mol Biol Cell. 1999 Aug;10(8):2703-34
  • Latest
    J:347774 Kolonay DW, et al., Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. Front Cell Dev Biol. 2024;12:1331563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory