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Eif3g Gene Detail
Summary
  • Symbol
    Eif3g
  • Name
    eukaryotic translation initiation factor 3, subunit G
  • Synonyms
    44kDa, D0Jmb4, Eif3s4, p44, TU-189B2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858258
    NCBI Gene: 53356
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:20805645-20809886 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 7.66 cM, cytoband A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858258
 protein coding gene Chr9:20805645-20809919 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034431
 protein coding gene Chr9:18063130-18067400 (-)
A/J MGP_AJ_G0034409
 protein coding gene Chr9:17768948-17773214 (-)
AKR/J MGP_AKRJ_G0034336
 protein coding gene Chr9:18087802-18092052 (-)
BALB/cJ MGP_BALBcJ_G0034400
 protein coding gene Chr9:17662382-17666630 (-)
C3H/HeJ MGP_C3HHeJ_G0034112
 protein coding gene Chr9:18399459-18403727 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034921
 protein coding gene Chr9:18777428-18781677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031851
 protein coding gene Chr9:16893734-16898124 (-)
CAST/EiJ MGP_CASTEiJ_G0033435
 protein coding gene Chr9:18219005-18223723 (-)
CBA/J MGP_CBAJ_G0034085
 protein coding gene Chr9:19501867-19506148 (-)
DBA/2J MGP_DBA2J_G0034244
 protein coding gene Chr9:17753524-17757772 (-)
FVB/NJ MGP_FVBNJ_G0034187
 protein coding gene Chr9:17257630-17261875 (-)
LP/J MGP_LPJ_G0034329
 protein coding gene Chr9:18242928-18247176 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034230
 protein coding gene Chr9:21124882-21129202 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034941
 protein coding gene Chr9:18040218-18044479 (-)
PWK/PhJ MGP_PWKPhJ_G0033141
 protein coding gene Chr9:17719151-17723399 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032975
 protein coding gene Chr9:18086395-18090600 (-)
WSB/EiJ MGP_WSBEiJ_G0033550
 protein coding gene Chr9:17768341-17772602 (-)



Homology
more
  • Human Ortholog
    EIF3G, eukaryotic translation initiation factor 3 subunit G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF3G, eukaryotic translation initiation factor 3 subunit G
  • Synonyms
    eIF3-delta, EIF3-P42, eIF3-p44, EIF3S4
  • Links
    NCBI Gene ID: 8666
    neXtProt AC: NX_O75821
    UniProt: O75821

  • Chr Location
    19p13.2; chr19:10115014-10119918 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    158
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 53356 NCBI Gene Model | MGI Sequence Detail 4242 C57BL/6J ±  kb
transcript NM_016876 RefSeq | MGI Sequence Detail 1068 C57BL/6  
polypeptide Q9Z1D1 UniProt | EBI | MGI Sequence Detail 320 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006979 eukaryotic translation initiation factor 3 subunit G
    (term hierarchy)
  • InterPro Domains
    IPR034240 eIF3G, RNA recognition motif
    IPR017334 Eukaryotic translation initiation factor 3 subunit G
    IPR024675 Eukaryotic translation initiation factor 3 subunit G, N-terminal
    IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    IPR035979 RNA-binding domain superfamily
    IPR000504 RNA recognition motif domain
  • GlyGen
    Q9Z1D1 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 158
    cDNA 158

    Microarray probesets 3
Other
Accession IDs
less
MGI:1206577
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:25193 Gordon HM, et al., Tumor necrosis factor induces genes involved in inflammation, cellular and tissue repair, and metabolism in murine fibroblasts. J Immunol. 1992 Jun 15;148(12):4021-7
  • Latest
    J:314131 Fujii K, et al., Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c. Dev Cell. 2021 Nov 8;56(21):2928-2937.e9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory