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Prl2c5 Gene Detail
Summary
  • Symbol
    Prl2c5
  • Name
    prolactin family 2, subfamily c, member 5
  • Synonyms
    MRP-4, Mrpplf4, PLF-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858413
    NCBI Gene: 107849
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:13357300-13366508 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 5.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858413
 protein coding gene Chr13:13357288-13366515 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020359
 protein coding gene Chr13:24953430-24976067 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020176
 protein coding gene Chr13:9780250-9795795 (-)
C3H/HeJ MGP_C3HHeJ_G0019982
 protein coding gene Chr13:9804781-9814929 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018380
 protein coding gene Chr13:23503754-23509979 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020113
 protein coding gene Chr13:27540291-27556551 (+)
DBA/2J MGP_DBA2J_G0020062
 protein coding gene Chr13:9232492-9453999 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019250
 protein coding gene Chr13:24028323-24041203 (+)
WSB/EiJ MGP_WSBEiJ_G0019576
 protein coding gene Chr13:9930519-9940102 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    13
  • cDNA Data
    24
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055360 Ensembl Gene Model | MGI Sequence Detail 9209 C57BL/6J ±  kb
transcript ENSMUST00000126540 Ensembl | MGI Sequence Detail 971 Not Applicable  
polypeptide ENSMUSP00000115024 Ensembl | MGI Sequence Detail 225 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR018116 Somatotropin hormone, conserved site
    IPR001400 Somatotropin/prolactin
  • GlyGen
    Q9JLV9 1 site
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 2
    Gene Ontology 4
  • Earliest
    J:61870 Fassett JT, et al., Mrp4, a new mitogen-regulated protein/proliferin gene; unique in this gene family for its expression in the adult mouse tail and ear. Endocrinology. 2000 May;141(5):1863-71
  • Latest
    J:332218 Sallais J, et al., HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2. JCI Insight. 2022 Dec 8;7(23)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory