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Cdc34b Gene Detail
Summary
  • Symbol
    Cdc34b
  • Name
    cell division cycle 34B
  • Synonyms
    Cdc34-ps
Location &
Maps
more
  • Sequence Map
    Chr11:94632663-94633840 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 58.92 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858429
 protein coding gene Chr11:94632608-94633859 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018968
 protein coding gene Chr11:96865994-96867633 (+)
A/J MGP_AJ_G0018936
 protein coding gene Chr11:92975756-92977007 (+)
AKR/J MGP_AKRJ_G0018906
 protein coding gene Chr11:95867707-95868958 (+)
BALB/cJ MGP_BALBcJ_G0018909
 protein coding gene Chr11:93422687-93425157 (+)
C3H/HeJ MGP_C3HHeJ_G0018723
 protein coding gene Chr11:95956919-95958170 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019361
 protein coding gene Chr11:99899126-99900377 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016992
 protein coding gene Chr11:90462948-90464195 (+)
CAST/EiJ MGP_CASTEiJ_G0018278
 protein coding gene Chr11:96684817-96686071 (+)
CBA/J MGP_CBAJ_G0018694
 protein coding gene Chr11:104031826-104033077 (+)
DBA/2J MGP_DBA2J_G0018802
 protein coding gene Chr11:92554678-92555929 (+)
FVB/NJ MGP_FVBNJ_G0018791
 protein coding gene Chr11:91973625-91975380 (+)
LP/J MGP_LPJ_G0018872
 protein coding gene Chr11:97400302-97403886 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018818
 protein coding gene Chr11:104028891-104030547 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019401
 protein coding gene Chr11:96104527-96105778 (+)
PWK/PhJ MGP_PWKPhJ_G0018048
 protein coding gene Chr11:93490100-93491472 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017838
 protein coding gene Chr11:95773735-95775438 (+)
WSB/EiJ MGP_WSBEiJ_G0018327
 protein coding gene Chr11:95980438-95983440 (+)



Homology
more
  • Human Ortholog
    CDC34, cell division cycle 34, ubiqiutin conjugating enzyme
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDC34, cell division cycle 34, ubiqiutin conjugating enzyme
  • Synonyms
    E2-CDC34, UBC3, UBCH3, UBE2R1
  • Links
    NCBI Gene ID: 997
    neXtProt AC: NX_P49427
    UniProt: P49427

  • Chr Location
    19p13.3; chr19:531760-542092 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    27
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 111266 NCBI Gene Model | MGI Sequence Detail 1178 C57BL/6J ±  kb
polypeptide A0A140T8I4 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050113 Ubiquitin-conjugating enzyme
    IPR023313 Ubiquitin-conjugating enzyme, active site
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 16
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:15595 Plon SE, et al., Cloning of the human homolog of the CDC34 cell cycle gene by complementation in yeast. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10484-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory