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Epb41l4b Gene Detail
Summary
  • Symbol
    Epb41l4b
  • Name
    erythrocyte membrane protein band 4.1 like 4b
  • Synonyms
    6430543G08Rik, D4Ertd346e, Ehm2, Epb4.1l4b, Lulu2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859149
    NCBI Gene: 54357
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:56991972-57143437 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 31.66 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4506 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859149
 protein coding gene Chr4:56991972-57143753 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028315
 protein coding gene Chr4:55767247-55922872 (-)
A/J MGP_AJ_G0028276
 protein coding gene Chr4:53640439-53793178 (-)
AKR/J MGP_AKRJ_G0028225
 protein coding gene Chr4:55124617-55279296 (-)
BALB/cJ MGP_BALBcJ_G0028295
 protein coding gene Chr4:53790652-53943815 (-)
C3H/HeJ MGP_C3HHeJ_G0028016
 protein coding gene Chr4:55627059-55783096 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028736
 protein coding gene Chr4:57752901-57914665 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026042
 protein coding gene Chr4:50435489-50586043 (-)
CAST/EiJ MGP_CASTEiJ_G0027454
 protein coding gene Chr4:55335397-55498379 (-)
CBA/J MGP_CBAJ_G0027981
 protein coding gene Chr4:59753422-59914067 (-)
DBA/2J MGP_DBA2J_G0028131
 protein coding gene Chr4:53542399-53693018 (-)
FVB/NJ MGP_FVBNJ_G0028098
 protein coding gene Chr4:52761795-52914877 (-)
LP/J MGP_LPJ_G0028230
 protein coding gene Chr4:55871630-56032930 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028122
 protein coding gene Chr4:62903117-63058599 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028772
 protein coding gene Chr4:55301347-55457867 (-)
PWK/PhJ MGP_PWKPhJ_G0027179
 protein coding gene Chr4:53526499-53683890 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027007
 protein coding gene Chr4:54569550-54731490 (-)
WSB/EiJ MGP_WSBEiJ_G0027532
 protein coding gene Chr4:55249957-55413961 (-)



Homology
more
  • Human Ortholog
    EPB41L4B, erythrocyte membrane protein band 4.1 like 4B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EPB41L4B, erythrocyte membrane protein band 4.1 like 4B
  • Synonyms
    CG1, EHM2, LULU2
  • Links
    NCBI Gene ID: 54566
    neXtProt AC: NX_Q9H329
    UniProt: Q9H329

  • Chr Location
    9q31.3; chr9:109171974-109321059 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    789
  • Tissues
    34
  • cDNA Data
    15
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028434 Ensembl Gene Model | MGI Sequence Detail 151466 C57BL/6J ±  kb
    transcript ENSMUST00000095076 Ensembl | MGI Sequence Detail 6746 Not Applicable  
    polypeptide ENSMUSP00000092687 Ensembl | MGI Sequence Detail 899 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 15
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1196220, MGI:2140462, MGI:2140630, MGI:2146773, MGI:2442740
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 9
    • Earliest
      J:36880 Hashimoto Y, et al., Identification of genes differentially expressed in association with metastatic potential of K-1735 murine melanoma by messenger RNA differential display. Cancer Res. 1996 Nov 15;56(22):5266-71
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory