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Ccdc22 Gene Detail
Summary
  • Symbol
    Ccdc22
  • Name
    coiled-coil domain containing 22
  • Synonyms
    DXImx40e, Sfc22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859608
    NCBI Gene: 54638
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:7460048-7471659 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 3.42 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    296 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859608
 protein coding gene ChrX:7460048-7471756 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035513
 protein coding gene ChrX:2205056-2216770 (-)
A/J MGP_AJ_G0035491
 protein coding gene ChrX:2166416-2178273 (-)
AKR/J MGP_AKRJ_G0035424
 protein coding gene ChrX:2268723-2280422 (-)
BALB/cJ MGP_BALBcJ_G0035487
 protein coding gene ChrX:2186024-2198069 (-)
C3H/HeJ MGP_C3HHeJ_G0035195
 protein coding gene ChrX:2240885-2252451 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036011
 protein coding gene ChrX:2283994-2295658 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032886
 protein coding gene ChrX:1735303-1747221 (-)
CAST/EiJ MGP_CASTEiJ_G0034495
 protein coding gene ChrX:2140877-2152557 (-)
CBA/J MGP_CBAJ_G0035165
 protein coding gene ChrX:2397198-2408904 (-)
DBA/2J MGP_DBA2J_G0035322
 protein coding gene ChrX:2188406-2200070 (-)
FVB/NJ MGP_FVBNJ_G0035269
 protein coding gene ChrX:2152193-2164014 (-)
LP/J MGP_LPJ_G0035399
 protein coding gene ChrX:2208100-2219753 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035308
 protein coding gene ChrX:2361619-2373260 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036029
 protein coding gene ChrX:2188683-2201456 (-)
PWK/PhJ MGP_PWKPhJ_G0034197
 protein coding gene ChrX:2119561-2131964 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034034
 protein coding gene ChrX:2159138-2170791 (-)
WSB/EiJ MGP_WSBEiJ_G0034618
 protein coding gene ChrX:2191932-2203629 (-)



Homology
more
  • Human Ortholog
    CCDC22, coiled-coil domain containing 22
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC22, coiled-coil domain containing 22
  • Synonyms
    CXorf37, JM1, RTSC2
  • Links
    NCBI Gene ID: 28952
    neXtProt AC: NX_O60826
    UniProt: O60826

  • Chr Location
    Xp11.23; chrX:49235470-49250520 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CCDC22 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54638 NCBI Gene Model | MGI Sequence Detail 11612 C57BL/6J ±  kb
transcript NM_138603 RefSeq | MGI Sequence Detail 2274 ZRU/MplStud  
polypeptide Q9JIG7 UniProt | EBI | MGI Sequence Detail 627 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 4
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147896
References
more
  • Summaries
    All 31
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
  • Latest
    J:236595 Bartuzi P, et al., CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016 Mar 11;7:10961
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory