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Ppp1r3f Gene Detail
Summary
  • Symbol
    Ppp1r3f
  • Name
    protein phosphatase 1, regulatory subunit 3F
  • Synonyms
    DXImx48e, RF3, Sfc15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859617
    NCBI Gene: 54646
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:7424815-7440541 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 3.40 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    289 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859617
protein coding gene ChrX:7423535-7440541 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035511
protein coding gene ChrX:2167414-2184366 (-)
A/J MGP_AJ_G0035489
protein coding gene ChrX:2128856-2146936 (-)
AKR/J MGP_AKRJ_G0035422
protein coding gene ChrX:2232328-2249286 (-)
BALB/cJ MGP_BALBcJ_G0035485
protein coding gene ChrX:2149148-2166088 (-)
C3H/HeJ MGP_C3HHeJ_G0035193
protein coding gene ChrX:2202225-2219147 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036009
protein coding gene ChrX:2244378-2261333 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032884
protein coding gene ChrX:1699536-1715656 (-)
CAST/EiJ MGP_CASTEiJ_G0034493
protein coding gene ChrX:2102933-2121454 (-)
CBA/J MGP_CBAJ_G0035163
protein coding gene ChrX:2358216-2375117 (-)
DBA/2J MGP_DBA2J_G0035320
protein coding gene ChrX:2150786-2167815 (-)
FVB/NJ MGP_FVBNJ_G0035267
protein coding gene ChrX:2115245-2132224 (-)
LP/J MGP_LPJ_G0035397
protein coding gene ChrX:2168729-2188231 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035306
protein coding gene ChrX:2324129-2341075 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036027
protein coding gene ChrX:2151215-2168111 (-)
PWK/PhJ MGP_PWKPhJ_G0034195
protein coding gene ChrX:2082294-2100020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034032
protein coding gene ChrX:2121544-2139808 (-)
WSB/EiJ MGP_WSBEiJ_G0034616
protein coding gene ChrX:2153937-2171696 (-)



Homology
more
  • Human Ortholog
    PPP1R3F, protein phosphatase 1 regulatory subunit 3F
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R3F, protein phosphatase 1 regulatory subunit 3F
  • Synonyms
    HB2E, LL0XNC01-7P3.1, R3F
  • Links
    NCBI Gene ID: 89801
    neXtProt AC: NX_Q6ZSY5
    UniProt: Q6ZSY5

  • Chr Location
    Xp11.23; chrX:49269793-49301469 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 54646 NCBI Gene Model | MGI Sequence Detail 15727 C57BL/6J ±  kb
transcript NM_001290574 RefSeq | MGI Sequence Detail 3499 ZRU/MplStud  
polypeptide Q9JIG4 UniProt | EBI | MGI Sequence Detail 799 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013129 protein phosphatase 1 regulatory subunit 3F
  • InterPro Domains
    IPR005036 CBM21 (carbohydrate binding type-21) domain
    IPR038175 CBM21 domain superfamily
    IPR050782 Protein phosphatase 1 regulatory subunit 3
  • GlyGen
    Q9JIG4 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 16
    Genomic 5
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:62168 Means GD, et al., A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation. Genomics. 2000 May 1;65(3):213-23
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory