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Fnbp4 Gene Detail
Summary
  • Symbol
    Fnbp4
  • Name
    formin binding protein 4
  • Synonyms
    FBP30
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860513
    NCBI Gene: 55935
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90575793-90611365 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 50.35 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    646 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860513
protein coding gene Chr2:90575714-90611365 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026131
protein coding gene Chr2:92016816-92055372 (+)
A/J MGP_AJ_G0026092
protein coding gene Chr2:88349290-88386945 (+)
AKR/J MGP_AKRJ_G0026073
protein coding gene Chr2:90792708-90830438 (+)
BALB/cJ MGP_BALBcJ_G0026101
protein coding gene Chr2:88505055-88545907 (+)
C3H/HeJ MGP_C3HHeJ_G0025852
protein coding gene Chr2:91067619-91105036 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026552
protein coding gene Chr2:95255311-95295781 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023942
protein coding gene Chr2:84874600-84909157 (+)
CAST/EiJ MGP_CASTEiJ_G0025317
protein coding gene Chr2:91574753-91616643 (+)
CBA/J MGP_CBAJ_G0025830
protein coding gene Chr2:98499990-98542916 (+)
DBA/2J MGP_DBA2J_G0025966
protein coding gene Chr2:87947313-87983977 (+)
FVB/NJ MGP_FVBNJ_G0025929
protein coding gene Chr2:87044282-87081664 (+)
LP/J MGP_LPJ_G0026070
protein coding gene Chr2:92226710-92265254 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025955
protein coding gene Chr2:101557487-101598863 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026606
protein coding gene Chr2:90840565-90878502 (+)
PWK/PhJ MGP_PWKPhJ_G0025052
protein coding gene Chr2:87668484-87704951 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024853
protein coding gene Chr2:90432749-90470690 (+)
WSB/EiJ MGP_WSBEiJ_G0025384
protein coding gene Chr2:91424506-91469379 (+)



Homology
more
  • Human Ortholog
    FNBP4, formin binding protein 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FNBP4, formin binding protein 4
  • Synonyms
    FBP30
  • Links
    NCBI Gene ID: 23360
    neXtProt AC: NX_Q8N3X1
    UniProt: Q8N3X1

  • Chr Location
    11p11.2; chr11:47716494-47767443 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 55935 NCBI Gene Model | MGI Sequence Detail 35573 C57BL/6J ±  kb
transcript NR_185311 RefSeq | MGI Sequence Detail 4606 C57BL/6  
polypeptide Q6ZQ03 UniProt | EBI | MGI Sequence Detail 1031 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5:e16087

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory