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Cpsf4 Gene Detail
Summary
  • Symbol
    Cpsf4
  • Name
    cleavage and polyadenylation specific factor 4
  • Synonyms
    30kDa
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861602
    NCBI Gene: 54188
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:145104023-145118851 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 85.08 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    473 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861602
 protein coding gene Chr5:145104023-145118851 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030360
 protein coding gene Chr5:150593597-150608447 (+)
A/J MGP_AJ_G0030329
 protein coding gene Chr5:144124760-144140106 (+)
AKR/J MGP_AKRJ_G0030261
 protein coding gene Chr5:148609591-148624428 (+)
BALB/cJ MGP_BALBcJ_G0030346
 protein coding gene Chr5:145380839-145397355 (+)
C3H/HeJ MGP_C3HHeJ_G0030057
 protein coding gene Chr5:149428262-149444035 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030791
 protein coding gene Chr5:156088328-156103392 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028012
 protein coding gene Chr5:137859977-137874919 (+)
CAST/EiJ MGP_CASTEiJ_G0029462
 protein coding gene Chr5:149001640-149016765 (+)
CBA/J MGP_CBAJ_G0030027
 protein coding gene Chr5:162529586-162544475 (+)
DBA/2J MGP_DBA2J_G0030177
 protein coding gene Chr5:143841351-143856343 (+)
FVB/NJ MGP_FVBNJ_G0030132
 protein coding gene Chr5:143076744-143092160 (+)
LP/J MGP_LPJ_G0030266
 protein coding gene Chr5:151178878-151193565 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030163
 protein coding gene Chr5:164838579-164853414 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030831
 protein coding gene Chr5:148511869-148527623 (+)
PWK/PhJ MGP_PWKPhJ_G0029177
 protein coding gene Chr5:142990567-143005539 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029013
 protein coding gene Chr5:146257455-146272167 (+)
WSB/EiJ MGP_WSBEiJ_G0029537
 protein coding gene Chr5:149316837-149332176 (+)



Homology
more
  • Human Ortholog
    CPSF4, cleavage and polyadenylation specific factor 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPSF4, cleavage and polyadenylation specific factor 4
  • Synonyms
    CPSF30, NAR, NEB-1, NEB1
  • Links
    NCBI Gene ID: 10898
    neXtProt AC: NX_O95639
    UniProt: O95639

  • Chr Location
    7q22.1; chr7:99438922-99457373 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    813
  • Tissues
    50
  • cDNA Data
    77
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54188 NCBI Gene Model | MGI Sequence Detail 14829 C57BL/6J ±  kb
transcript NM_001374716 RefSeq | MGI Sequence Detail 1783 C57BL/6  
polypeptide Q8BQZ5 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 77
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2141311
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory