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Tssc4 Gene Detail
Summary
  • Symbol
    Tssc4
  • Name
    tumor-suppressing subchromosomal transferable fragment 4
  • Synonyms
    ESTM671070
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861712
    NCBI Gene: 56844
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:142622986-142624830 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.11 cM
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861712
 protein coding gene Chr7:142621049-142624830 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033270
 protein coding gene Chr7:148350125-148351969 (+)
A/J MGP_AJ_G0033253
 protein coding gene Chr7:144051364-144053208 (+)
AKR/J MGP_AKRJ_G0033184
 protein coding gene Chr7:148101713-148103557 (+)
BALB/cJ MGP_BALBcJ_G0033253
 protein coding gene Chr7:143827576-143829420 (+)
C3H/HeJ MGP_C3HHeJ_G0032969
 protein coding gene Chr7:147864371-147866215 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033763
 protein coding gene Chr7:153713910-153715754 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030736
 protein coding gene Chr7:145264634-145266477 (+)
CAST/EiJ MGP_CASTEiJ_G0032291
 protein coding gene Chr7:140167744-140169581 (+)
CBA/J MGP_CBAJ_G0032940
 protein coding gene Chr7:158973571-158975415 (+)
DBA/2J MGP_DBA2J_G0033094
 protein coding gene Chr7:142025679-142027523 (+)
FVB/NJ MGP_FVBNJ_G0033042
 protein coding gene Chr7:141946301-141948145 (+)
LP/J MGP_LPJ_G0033186
 protein coding gene Chr7:149868963-149870807 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033076
 protein coding gene Chr7:159568889-159570733 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033783
 protein coding gene Chr7:147065038-147066882 (+)
PWK/PhJ MGP_PWKPhJ_G0032000
 protein coding gene Chr7:135328330-135330173 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031846
 protein coding gene Chr7:133870926-133872770 (+)
WSB/EiJ MGP_WSBEiJ_G0032403
 protein coding gene Chr7:148065580-148067424 (+)



Homology
more
  • Human Ortholog
    TSSC4, tumor suppressing subtransferable candidate 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSSC4, tumor suppressing subtransferable candidate 4
  • Links
    NCBI Gene ID: 10078
    neXtProt AC: NX_Q9Y5U2
    UniProt: Q9Y5U2

  • Chr Location
    11p15.5; chr11:2400488-2403878 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    16
  • cDNA Data
    92
  • Literature Summary
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045752 Ensembl Gene Model | MGI Sequence Detail 1845 C57BL/6J ±  kb
transcript ENSMUST00000060433 Ensembl | MGI Sequence Detail 1519 Not Applicable  
polypeptide ENSMUSP00000056582 Ensembl | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016769 U5 small nuclear ribonucleoprotein TSSC4
    (term hierarchy)
  • InterPro Domains
    IPR029338 Tumour suppressing sub-chromosomal transferable candidate 4
  • GlyGen
    Q9JHE7 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 107
    Genomic 10
    cDNA 92
    Primer pair 5

    Microarray probesets 3
Other
Accession IDs
less
MGI:1342282
References
more
  • Summaries
    All 46
    Developmental Gene Expression 14
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:10529 Bastian H, et al., A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]. EMBO J. 1990 Jun;9(6):1839-52
  • Latest
    J:266304 Bogutz AB, et al., Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. PLoS Genet. 2018 Aug;14(8):e1007587
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory