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Gipc2 Gene Detail
Summary
  • Symbol
    Gipc2
  • Name
    GIPC PDZ domain containing family, member 2
  • Synonyms
    2200002N01Rik, Semcap2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889209
    NCBI Gene: 54120
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:151799476-151871537 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 76.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2309 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889209
 protein coding gene Chr3:151799170-151871867 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027986
 protein coding gene Chr3:155932739-156007649 (-)
A/J MGP_AJ_G0027945
 protein coding gene Chr3:150283772-150358190 (-)
AKR/J MGP_AKRJ_G0027911
 protein coding gene Chr3:154236988-154316681 (-)
BALB/cJ MGP_BALBcJ_G0027957
 protein coding gene Chr3:150121781-150195973 (-)
C3H/HeJ MGP_C3HHeJ_G0027687
 protein coding gene Chr3:154682320-154760002 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028400
 protein coding gene Chr3:161076937-161159957 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025738
 protein coding gene Chr3:145121470-145194495 (-)
CAST/EiJ MGP_CASTEiJ_G0027140
 protein coding gene Chr3:154753133-154832115 (-)
CBA/J MGP_CBAJ_G0027662
 protein coding gene Chr3:166843808-166947763 (-)
DBA/2J MGP_DBA2J_G0027802
 protein coding gene Chr3:149390980-149465084 (-)
FVB/NJ MGP_FVBNJ_G0027769
 protein coding gene Chr3:146766831-146842724 (-)
LP/J MGP_LPJ_G0027913
 protein coding gene Chr3:157305090-157386716 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027802
 protein coding gene Chr3:175394641-175474212 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028459
 protein coding gene Chr3:153932173-154010123 (-)
PWK/PhJ MGP_PWKPhJ_G0026863
 protein coding gene Chr3:149272138-149348513 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026691
 protein coding gene Chr3:152086465-152168632 (-)
WSB/EiJ MGP_WSBEiJ_G0027220
 protein coding gene Chr3:154940481-155020340 (-)



Homology
more
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GIPC2, GIPC PDZ domain containing family member 2
  • Synonyms
    SEMCAP-2, SEMCAP2
  • Links
    NCBI Gene ID: 54810
    neXtProt AC: NX_Q8TF65
    UniProt: Q8TF65

  • Chr Location
    1p31.1; chr1:77979542-78138444 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    757
  • Tissues
    21
  • cDNA Data
    36
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 54120 NCBI Gene Model | MGI Sequence Detail 72062 C57BL/6J ±  kb
    transcript NM_016867 RefSeq | MGI Sequence Detail 1286 Not Specified  
    polypeptide Q9Z2H7 UniProt | EBI | MGI Sequence Detail 314 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 41
      cDNA 40
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1913531, MGI:2139885
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:64422 Wang LH, et al., A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF. J Biol Chem. 1999 May 14;274(20):14137-46
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory