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Pramel1 Gene Detail
Summary
  • Symbol
    Pramel1
  • Name
    PRAME like 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890541
    NCBI Gene: 83491
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:143120998-143126730 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 77.64 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    57 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890541
 protein coding gene Chr4:143120889-143126730 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029068
 protein coding gene Chr4:146619643-146626858 (+)
A/J MGP_AJ_G0029028
 protein coding gene Chr4:140233596-140239311 (+)
AKR/J MGP_AKRJ_G0028980
 protein coding gene Chr4:144273752-144279477 (+)
BALB/cJ MGP_BALBcJ_G0029052
 protein coding gene Chr4:140899087-140904819 (+)
C3H/HeJ MGP_C3HHeJ_G0028766
 protein coding gene Chr4:144654518-144660248 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029493
 protein coding gene Chr4:151650820-151656531 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026763
 protein coding gene Chr4:133075276-133081005 (+)
CAST/EiJ MGP_CASTEiJ_G0028198
 protein coding gene Chr4:142956144-142961842 (+)
CBA/J MGP_CBAJ_G0028730
 protein coding gene Chr4:156210439-156216146 (+)
DBA/2J MGP_DBA2J_G0028880
 protein coding gene Chr4:140576451-140582169 (+)
FVB/NJ MGP_FVBNJ_G0028847
 protein coding gene Chr4:139744211-139749929 (+)
LP/J MGP_LPJ_G0028979
 protein coding gene Chr4:146653995-146659886 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028873
 protein coding gene Chr4:159862715-159868433 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029531
 protein coding gene Chr4:144821846-144827585 (+)
PWK/PhJ MGP_PWKPhJ_G0027920
 protein coding gene Chr4:137499510-137505753 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027743
 protein coding gene Chr4:140647126-140652864 (+)
WSB/EiJ MGP_WSBEiJ_G0028276
 protein coding gene Chr4:145124425-145130143 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041805 Ensembl Gene Model | MGI Sequence Detail 5733 C57BL/6J ±  kb
    transcript ENSMUST00000037419 Ensembl | MGI Sequence Detail 2794 Not Applicable  
    polypeptide ENSMUSP00000043718 Ensembl | MGI Sequence Detail 458 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR032675 Leucine-rich repeat domain superfamily
      IPR026271 PRAME
      IPR050694 PRAME domain-containing protein
    Molecular
    Reagents
    less
    • All nucleic 6
      Genomic 2
      cDNA 3
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 26
      Gene Ontology 4
      Phenotypes 6
    • Earliest
      J:68614 Wang PJ, et al., An abundance of X-linked genes expressed in spermatogonia. Nat Genet. 2001 Apr;27(4):422-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory