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Evi2b Gene Detail
Summary
  • Symbol
    Evi2b
  • Name
    ecotropic viral integration site 2b
  • Synonyms
    Evi2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890682
    NCBI Gene: 216984
  • Alliance
    gene page
  • Transcription Start Sites
    24 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:79405882-79414588 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 46.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890682
 protein coding gene Chr11:79404211-79414588 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018799
 protein coding gene Chr11:80623459-80632175 (-)
A/J MGP_AJ_G0018766
 protein coding gene Chr11:77520438-77529146 (-)
AKR/J MGP_AKRJ_G0018736
 protein coding gene Chr11:79847563-79856246 (-)
BALB/cJ MGP_BALBcJ_G0018739
 protein coding gene Chr11:77928936-77937729 (-)
C3H/HeJ MGP_C3HHeJ_G0018553
 protein coding gene Chr11:79905487-79914873 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019191
 protein coding gene Chr11:83100940-83109574 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016825
 protein coding gene Chr11:74467062-74475592 (-)
CAST/EiJ MGP_CASTEiJ_G0018108
 protein coding gene Chr11:80374142-80384289 (-)
CBA/J MGP_CBAJ_G0018524
 protein coding gene Chr11:86719448-86728345 (-)
DBA/2J MGP_DBA2J_G0018632
 protein coding gene Chr11:77071615-77080315 (-)
FVB/NJ MGP_FVBNJ_G0018621
 protein coding gene Chr11:76669410-76678090 (-)
LP/J MGP_LPJ_G0018702
 protein coding gene Chr11:81132073-81143921 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018648
 protein coding gene Chr11:87016979-87027962 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019231
 protein coding gene Chr11:80108646-80117334 (-)
PWK/PhJ MGP_PWKPhJ_G0017878
 protein coding gene Chr11:77887978-77896626 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017669
 protein coding gene Chr11:79712755-79722744 (-)
WSB/EiJ MGP_WSBEiJ_G0018160
 protein coding gene Chr11:79933189-79941896 (-)



Homology
more
  • Human Ortholog
    EVI2B, ecotropic viral integration site 2B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EVI2B, ecotropic viral integration site 2B
  • Synonyms
    CD361, D17S376, EVDB
  • Links
    NCBI Gene ID: 2124
    neXtProt AC: NX_P34910
    UniProt: P34910

  • Chr Location
    17q11.2; chr17:31303770-31314105 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Evi2b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    10 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    787
  • Tissues
    40
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000093938 Ensembl Gene Model | MGI Sequence Detail 8707 C57BL/6J ±  kb
transcript ENSMUST00000179322 Ensembl | MGI Sequence Detail 1858 Not Applicable  
polypeptide ENSMUSP00000136153 Ensembl | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory