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Ndufs5 Gene Detail
Summary
  • Symbol
    Ndufs5
  • Name
    NADH:ubiquinone oxidoreductase core subunit S5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890889
    NCBI Gene: 595136
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:123606503-123611979 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 57.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    311 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890889
 protein coding gene Chr4:123606503-123611995 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028742
 protein coding gene Chr4:125192241-125197375 (-)
A/J MGP_AJ_G0028701
 protein coding gene Chr4:120304141-120310389 (-)
AKR/J MGP_AKRJ_G0028654
 protein coding gene Chr4:123572213-123586813 (-)
BALB/cJ MGP_BALBcJ_G0028724
 protein coding gene Chr4:120867949-120873415 (-)
C3H/HeJ MGP_C3HHeJ_G0028439
 protein coding gene Chr4:123670034-123676036 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029165
 protein coding gene Chr4:130005583-130012580 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026438
 protein coding gene Chr4:113498443-113504283 (-)
CAST/EiJ MGP_CASTEiJ_G0027871
 protein coding gene Chr4:121700981-121708178 (-)
CBA/J MGP_CBAJ_G0028404
 protein coding gene Chr4:133298750-133304911 (-)
DBA/2J MGP_DBA2J_G0028553
 protein coding gene Chr4:120784872-120794299 (-)
FVB/NJ MGP_FVBNJ_G0028520
 protein coding gene Chr4:119413953-119420364 (-)
LP/J MGP_LPJ_G0028654
 protein coding gene Chr4:125470551-125479007 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028546
 protein coding gene Chr4:138251244-138256566 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029203
 protein coding gene Chr4:123944708-123951089 (-)
PWK/PhJ MGP_PWKPhJ_G0027591
 protein coding gene Chr4:117183238-117189268 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027418
 protein coding gene Chr4:119735347-119742723 (-)
WSB/EiJ MGP_WSBEiJ_G0027950
 protein coding gene Chr4:124004686-124011585 (-)



Homology
more
  • Human Ortholog
    NDUFS5, NADH:ubiquinone oxidoreductase subunit S5
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFS5, NADH:ubiquinone oxidoreductase subunit S5
  • Synonyms
    CI-15k, CI15K
  • Links
    NCBI Gene ID: 4725
    neXtProt AC: NX_O43920
    UniProt: O43920

  • Chr Location
    1p34.3; chr1:39026318-39034636 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Ndufs5
  • Find Mice (IMSR)
    7 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    9
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    84
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 595136 NCBI Gene Model | MGI Sequence Detail 5477 C57BL/6J ±  kb
transcript NM_001030274 RefSeq | MGI Sequence Detail 540 C57BL/6  
polypeptide Q99LY9 UniProt | EBI | MGI Sequence Detail 106 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 84
    cDNA 84

    Microarray probesets 3
Other
Accession IDs
less
MGI:2146398
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 9
    Phenotypes 12
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory