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Psg21 Gene Detail
Summary
  • Symbol
    Psg21
  • Name
    pregnancy-specific beta-1-glycoprotein 21
  • Synonyms
    1600019C01Rik, 1600025N01Rik, 1600026N13Rik, cea8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891353
    NCBI Gene: 72242
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18380661-18390650 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    498 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891353
protein coding gene Chr7:18380579-18390650 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0031642
protein coding gene Chr7:16688768-16731459 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0031441
protein coding gene Chr7:16636456-16839694 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032187
protein coding gene Chr7:17412855-17458914 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0031404
protein coding gene Chr7:17838020-17957931 (-)
DBA/2J MGP_DBA2J_G0031561
protein coding gene Chr7:15994252-16323618 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0031642
protein coding gene Chr7:16650705-16799063 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031549
protein coding gene Chr7:17774108-17875016 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032218
protein coding gene Chr7:16311293-16504543 (-)
PWK/PhJ MGP_PWKPhJ_G0030514
protein coding gene Chr7:13306047-13308601 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030341
protein coding gene Chr7:10983493-10986027 (-)
WSB/EiJ MGP_WSBEiJ_G0030887
protein coding gene Chr7:16343046-16345600 (-)



Homology
more
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Vertebrate Orthologs
    23
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Synonyms
    CGM7, CGM7_HUMAN, NCA
  • Links
    NCBI Gene ID: 1089
    neXtProt AC: NX_O75871
    UniProt: O75871

  • Chr Location
    19q13.2; chr19:41613436-41627074 (-)  GRCh38

  • Human Ortholog
    CEACAM7, CEA cell adhesion molecule 7
  • Synonyms
    CGM2
  • Links
    NCBI Gene ID: 1087
    neXtProt AC: NX_Q14002
    UniProt: Q14002

  • Chr Location
    19q13.2; chr19:41673303-41706976 (-)  GRCh38

  • Human Ortholog
    PSG5, pregnancy specific beta-1-glycoprotein 5
  • Synonyms
    FL-NCA-3, PSG
  • Links
    NCBI Gene ID: 5673
    neXtProt AC: NX_Q15238
    UniProt: Q15238

  • Chr Location
    19q13.31; chr19:43166256-43186536 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070796 Ensembl Gene Model | MGI Sequence Detail 9990 C57BL/6J ±  kb
transcript ENSMUST00000094793 Ensembl | MGI Sequence Detail 2074 Not Applicable  
polypeptide ENSMUSP00000092387 Ensembl | MGI Sequence Detail 471 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR050831 Carcinoembryonic antigen-related cell adhesion
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR003598 Immunoglobulin subtype 2
    IPR013106 Immunoglobulin V-set domain
  • GlyGen
    Q9DAV5 2 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 107
    cDNA 106
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917617, MGI:1917618, MGI:1919492
References
more
  • Summaries
    All 28
    Developmental Gene Expression 8
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:333829 Lopez-Tello J, et al., Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. Front Endocrinol (Lausanne). 2023;14:1116770

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory