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Gpr137b Gene Detail
Summary
  • Symbol
    Gpr137b
  • Name
    G protein-coupled receptor 137B
  • Synonyms
    2310041G17Rik, C80741, Tm7sf1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891463
    NCBI Gene: 83924
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:13532205-13568599 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 5.24 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    14
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891463
 protein coding gene Chr13:13528035-13568599 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020190
 protein coding gene Chr13:9211719-9259552 (-)
AKR/J MGP_AKRJ_G0020165
 protein coding gene Chr13:10231513-10336047 (-)
BALB/cJ MGP_BALBcJ_G0020173
 protein coding gene Chr13:9201314-9254277 (-)
C3H/HeJ MGP_C3HHeJ_G0019978
 protein coding gene Chr13:9559401-9567825 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020621
 protein coding gene Chr13:10774866-10787690 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018227
 protein coding gene Chr13:9030306-9068172 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0019945
 protein coding gene Chr13:11082003-11181177 (-)
DBA/2J MGP_DBA2J_G0020064
 protein coding gene Chr13:9834900-9879722 (-)
FVB/NJ MGP_FVBNJ_G0020046
 protein coding gene Chr13:8841911-8852725 (-)
LP/J MGP_LPJ_G0020135
 protein coding gene Chr13:9512589-9567997 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0020648
 protein coding gene Chr13:10099200-10116734 (-)
PWK/PhJ MGP_PWKPhJ_G0019278
 protein coding gene Chr13:9966486-10007538 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019085
 protein coding gene Chr13:9300819-9338248 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    GPR137B, G protein-coupled receptor 137B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR137B, G protein-coupled receptor 137B
  • Synonyms
    TM7SF1
  • Links
    NCBI Gene ID: 7107
    neXtProt AC: NX_O60478
    UniProt: O60478

  • Chr Location
    1q42.3; chr1:236142505-236221865 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    824
  • Tissues
    76
  • cDNA Data
    15
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021306 Ensembl Gene Model | MGI Sequence Detail 36395 C57BL/6J ±  kb
transcript ENSMUST00000223093 Ensembl | MGI Sequence Detail 2351 Not Applicable  
polypeptide ENSMUSP00000152434 Ensembl | MGI Sequence Detail 393 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 1
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-34030, MGI:106338, MGI:1917401, MGI:2145288, MGI:2145337, MGI:2145451, MGI:2145516, MGI:2145518
References
more
  • Summaries
    All 53
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:34960 Chambers DM, et al., Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains. Genome Res. 1996 Aug;6(8):715-23
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory