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Slc28a2 Gene Detail
Summary
  • Symbol
    Slc28a2
  • Name
    solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
  • Synonyms
    2010208B10Rik, CNT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913105
    NCBI Gene: 269346
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:122256958-122291618 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.63 cM, cytoband E3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    984 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913105
 protein coding gene Chr2:122256836-122291633 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026416
 protein coding gene Chr2:125457539-125554774 (+)
A/J MGP_AJ_G0026377
 protein coding gene Chr2:120310653-120419401 (+)
AKR/J MGP_AKRJ_G0026354
 protein coding gene Chr2:123729825-123808461 (+)
BALB/cJ MGP_BALBcJ_G0026390
 protein coding gene Chr2:120650105-120706021 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0026836
 protein coding gene Chr2:129566196-129648380 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026114
 protein coding gene Chr2:134137019-134225651 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0026352
 protein coding gene Chr2:125661468-125796936 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026232
 protein coding gene Chr2:138273986-138417749 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025133
 protein coding gene Chr2:122993461-123014318 (+)
WSB/EiJ MGP_WSBEiJ_G0025668
 protein coding gene Chr2:124719539-124791038 (+)



Homology
more
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC28A2, solute carrier family 28 member 2
  • Synonyms
    CNT2, HCNT2, HsT17153, SPNT1
  • Links
    NCBI Gene ID: 9153
    neXtProt AC: NX_O43868
    UniProt: O43868

  • Chr Location
    15q21.1; chr15:45252234-45277846 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    3
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027219 Ensembl Gene Model | MGI Sequence Detail 34661 C57BL/6J ±  kb
transcript ENSMUST00000110525 Ensembl | MGI Sequence Detail 3911 Not Applicable  
polypeptide ENSMUSP00000106154 Ensembl | MGI Sequence Detail 660 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015052 sodium/nucleoside cotransporter 2
    (term hierarchy)
  • InterPro Domains
    IPR008276 Concentrative nucleoside transporter
    IPR011657 Concentrative nucleoside transporter C-terminal domain
    IPR018270 Concentrative nucleoside transporter, metazoan/bacterial
    IPR002668 Concentrative nucleoside transporter N-terminal domain
    IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain
  • GlyGen
    O88627 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 13
    Genomic 1
    cDNA 10
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1919339, MGI:2139438
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory