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Sdhaf3 Gene Detail
Summary
  • Symbol
    Sdhaf3
  • Name
    succinate dehydrogenase complex assembly factor 3
  • Synonyms
    0610005M07Rik, 4933430A16Rik, Acn9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913288
    NCBI Gene: 71238
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:6956004-7039661 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 2.83 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1963 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913288
 protein coding gene Chr6:6956004-7042979 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030442
 protein coding gene Chr6:3877736-3951863 (+)
A/J MGP_AJ_G0030415
 protein coding gene Chr6:3730912-3815871 (+)
AKR/J MGP_AKRJ_G0030342
 protein coding gene Chr6:3835484-3916577 (+)
BALB/cJ MGP_BALBcJ_G0030424
 protein coding gene Chr6:3684571-3771791 (+)
C3H/HeJ MGP_C3HHeJ_G0030138
 protein coding gene Chr6:3780420-3859958 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030879
 protein coding gene Chr6:3972818-4066827 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028090
 protein coding gene Chr6:3347218-3406969 (+)
CAST/EiJ MGP_CASTEiJ_G0029539
 protein coding gene Chr6:3797747-3857778 (+)
CBA/J MGP_CBAJ_G0030116
 protein coding gene Chr6:4105671-4196917 (+)
DBA/2J MGP_DBA2J_G0030260
 protein coding gene Chr6:3668742-3754062 (+)
FVB/NJ MGP_FVBNJ_G0030214
 protein coding gene Chr6:3657553-3739989 (+)
LP/J MGP_LPJ_G0030347
 protein coding gene Chr6:3832606-3924569 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030250
 protein coding gene Chr6:4148483-4239905 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030909
 protein coding gene Chr6:3778243-3872791 (+)
PWK/PhJ MGP_PWKPhJ_G0029254
 protein coding gene Chr6:3609743-3675598 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029090
 protein coding gene Chr6:3825643-3895618 (+)
WSB/EiJ MGP_WSBEiJ_G0029616
 protein coding gene Chr6:3772887-3838843 (+)



Homology
more
  • Human Ortholog
    SDHAF3, succinate dehydrogenase complex assembly factor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SDHAF3, succinate dehydrogenase complex assembly factor 3
  • Synonyms
    ACN9, DC11, LYRM10, Sdh7
  • Links
    NCBI Gene ID: 57001
    neXtProt AC: NX_Q9NRP4
    UniProt: Q9NRP4

  • Chr Location
    7q21.3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71238 NCBI Gene Model | MGI Sequence Detail 83658 C57BL/6J ±  kb
transcript NR_184565 RefSeq | MGI Sequence Detail 1139 C57BL/6  
polypeptide Q8BQU3 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:1918488
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:54377 Dennis RA, et al., Acn9 is a novel protein of gluconeogenesis that is located in the mitochondrial intermembrane space. Eur J Biochem. 1999 Apr;261(1):236-43
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory