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Chchd6 Gene Detail
Summary
  • Symbol
    Chchd6
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 6
  • Synonyms
    0710001P09Rik, 1700021B03Rik, Micos25
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913348
    NCBI Gene: 66098
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:89360128-89572634 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 39.91 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913348
 protein coding gene Chr6:89360128-89572634 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031020
 protein coding gene Chr6:90834068-91049127 (-)
A/J MGP_AJ_G0030986
 protein coding gene Chr6:87378842-87590451 (-)
AKR/J MGP_AKRJ_G0030917
 protein coding gene Chr6:89846944-90058519 (-)
BALB/cJ MGP_BALBcJ_G0030999
 protein coding gene Chr6:87352184-87560711 (-)
C3H/HeJ MGP_C3HHeJ_G0030711
 protein coding gene Chr6:94399778-94603156 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031456
 protein coding gene Chr6:93275422-93489685 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028637
 protein coding gene Chr6:85446602-85650201 (-)
CAST/EiJ MGP_CASTEiJ_G0030108
 protein coding gene Chr6:89952614-90164419 (-)
CBA/J MGP_CBAJ_G0030683
 protein coding gene Chr6:96777359-96990703 (-)
DBA/2J MGP_DBA2J_G0030839
 protein coding gene Chr6:86616474-86821419 (-)
FVB/NJ MGP_FVBNJ_G0030792
 protein coding gene Chr6:85818944-86024118 (-)
LP/J MGP_LPJ_G0030916
 protein coding gene Chr6:90864753-91076068 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030825
 protein coding gene Chr6:100917133-101127738 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031483
 protein coding gene Chr6:89692157-89898483 (-)
PWK/PhJ MGP_PWKPhJ_G0029823
 protein coding gene Chr6:85592672-85800988 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029651
 protein coding gene Chr6:88527177-88757154 (-)
WSB/EiJ MGP_WSBEiJ_G0030189
 protein coding gene Chr6:90140398-90353667 (-)



Homology
more
  • Human Ortholog
    CHCHD6, coiled-coil-helix-coiled-coil-helix domain containing 6
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHCHD6, coiled-coil-helix-coiled-coil-helix domain containing 6
  • Synonyms
    CHCM1, Mic25, MICOS25, PPP1R23
  • Links
    NCBI Gene ID: 84303
    neXtProt AC: NX_Q9BRQ6
    UniProt: Q9BRQ6

  • Chr Location
    3q21.3; chr3:126704240-126960420 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    61
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66098 NCBI Gene Model | MGI Sequence Detail 212507 C57BL/6J ±  kb
transcript NM_025351 RefSeq | MGI Sequence Detail 1126 C57BL/6  
polypeptide Q91VN4 UniProt | EBI | MGI Sequence Detail 273 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916633
References
more
  • Summaries
    All 35
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory