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Tmed3 Gene Detail
Summary
  • Symbol
    Tmed3
  • Name
    transmembrane p24 trafficking protein 3
  • Synonyms
    1200002G13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913361
    NCBI Gene: 66111
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:89581256-89587096 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 47.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    303 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913361
 protein coding gene Chr9:89581256-89587121 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035116
 protein coding gene Chr9:90628858-90634718 (-)
A/J MGP_AJ_G0035097
 protein coding gene Chr9:87488645-87494505 (-)
AKR/J MGP_AKRJ_G0035029
 protein coding gene Chr9:89549919-89555782 (-)
BALB/cJ MGP_BALBcJ_G0035089
 protein coding gene Chr9:87134578-87140438 (-)
C3H/HeJ MGP_C3HHeJ_G0034800
 protein coding gene Chr9:89985199-89991059 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035610
 protein coding gene Chr9:93147399-93153262 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032513
 protein coding gene Chr9:85670400-85676344 (-)
CAST/EiJ MGP_CASTEiJ_G0034112
 protein coding gene Chr9:89755412-89766644 (-)
CBA/J MGP_CBAJ_G0034768
 protein coding gene Chr9:96368966-96374886 (-)
DBA/2J MGP_DBA2J_G0034930
 protein coding gene Chr9:87036854-87042771 (-)
FVB/NJ MGP_FVBNJ_G0034876
 protein coding gene Chr9:86053995-86059895 (-)
LP/J MGP_LPJ_G0035009
 protein coding gene Chr9:90845071-90850931 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034917
 protein coding gene Chr9:98002307-98008170 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035630
 protein coding gene Chr9:89766618-89772533 (-)
PWK/PhJ MGP_PWKPhJ_G0033819
 protein coding gene Chr9:87193854-87200578 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033653
 protein coding gene Chr9:89824254-89830104 (-)
WSB/EiJ MGP_WSBEiJ_G0034232
 protein coding gene Chr9:89648775-89654701 (-)



Homology
more
  • Human Ortholog
    TMED3, transmembrane p24 trafficking protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED3, transmembrane p24 trafficking protein 3
  • Synonyms
    C15orf22, P24B, p24g4, p24gamma4, p26
  • Links
    NCBI Gene ID: 23423
    neXtProt AC: NX_Q9Y3Q3
    UniProt: Q9Y3Q3

  • Chr Location
    15q25.1; chr15:79311112-79427432 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    948
  • Tissues
    45
  • cDNA Data
    145
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66111 NCBI Gene Model | MGI Sequence Detail 5841 C57BL/6J ±  kb
    transcript NM_025360 RefSeq | MGI Sequence Detail 1324 C57BL/6  
    polypeptide Q78IS1 UniProt | EBI | MGI Sequence Detail 221 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 145
      cDNA 145

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2143317
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory