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Mustn1 Gene Detail
Summary
  • Symbol
    Mustn1
  • Name
    musculoskeletal, embryonic nuclear protein 1
  • Synonyms
    1110028G01Rik, Mustang
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913425
    NCBI Gene: 66175
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:30601214-30603567 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 19.09 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913425
 protein coding gene Chr14:30601157-30603567 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021109
 protein coding gene Chr14:24023931-24026282 (+)
A/J MGP_AJ_G0021057
 protein coding gene Chr14:23132529-23134883 (+)
AKR/J MGP_AKRJ_G0021034
 protein coding gene Chr14:24241444-24243809 (+)
BALB/cJ MGP_BALBcJ_G0021061
 protein coding gene Chr14:23231538-23233954 (+)
C3H/HeJ MGP_C3HHeJ_G0020844
 protein coding gene Chr14:24103555-24105906 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021493
 protein coding gene Chr14:24985159-24987510 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019056
 protein coding gene Chr14:23189607-23191961 (+)
CAST/EiJ MGP_CASTEiJ_G0020369
 protein coding gene Chr14:23856205-23858561 (+)
CBA/J MGP_CBAJ_G0020811
 protein coding gene Chr14:25937975-25940337 (+)
DBA/2J MGP_DBA2J_G0020933
 protein coding gene Chr14:23156964-23159315 (+)
FVB/NJ MGP_FVBNJ_G0020917
 protein coding gene Chr14:23114058-23116420 (+)
LP/J MGP_LPJ_G0021002
 protein coding gene Chr14:24354131-24356482 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020943
 protein coding gene Chr14:25218294-25220649 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021526
 protein coding gene Chr14:23994872-23997222 (+)
PWK/PhJ MGP_PWKPhJ_G0020117
 protein coding gene Chr14:22605282-22607678 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019941
 protein coding gene Chr14:23579245-23581552 (+)
WSB/EiJ MGP_WSBEiJ_G0020424
 protein coding gene Chr14:24055792-24058145 (+)



Homology
more
  • Human Ortholog
    MUSTN1, musculoskeletal, embryonic nuclear protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MUSTN1, musculoskeletal, embryonic nuclear protein 1
  • Synonyms
    MUSTANG
  • Links
    NCBI Gene ID: 389125
    neXtProt AC: NX_Q8IVN3
    UniProt: Q8IVN3

  • Chr Location
    3p21.1; chr3:52833114-52835019 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null females show higher collagen content after chemically induced muscle injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    36
  • cDNA Data
    29
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66175 NCBI Gene Model | MGI Sequence Detail 2354 C57BL/6J ±  kb
    transcript NM_181390 RefSeq | MGI Sequence Detail 1194 C57BL/6  
    polypeptide Q99JI1 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      cDNA 29
      Primer pair 1
      Other 3

      Microarray probesets 4
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:346460 Ducommun S, et al., Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. Mol Metab. 2024 Mar 6;82:101912
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory