Cd302 MGI Mouse Gene Detail - MGI:1913455

Symbol

Cd302
Name

CD302 antigen
Synonyms

1110055L24Rik

Feature Type

protein coding gene
IDs

MGI:1913455
NCBI Gene: 66205
Alliance

gene page
Transcription Start Sites

8 TSS

Sequence Map

Chr2:60082337-60114828 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 34.50 cM
Mapping Data

2 experiments

SNPs within 2kb

937 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913455	protein coding gene	Chr2:60082337-60114832 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0025760	protein coding gene	Chr2:59833436-59869291 (-)
A/J	MGP_AJ_G0025736	protein coding gene	Chr2:57527303-57561332 (-)
AKR/J	MGP_AKRJ_G0025706	protein coding gene	Chr2:59098380-59138217 (-)
BALB/cJ	MGP_BALBcJ_G0025731	protein coding gene	Chr2:57631194-57664256 (-)
C3H/HeJ	MGP_C3HHeJ_G0025492	protein coding gene	Chr2:59210794-59246275 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0026178	protein coding gene	Chr2:61596594-61631004 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023582	protein coding gene	Chr2:55111535-55142346 (-)
CAST/EiJ	MGP_CASTEiJ_G0024956	protein coding gene	Chr2:59251099-59284815 (-)
CBA/J	MGP_CBAJ_G0025472	protein coding gene	Chr2:63938409-63979546 (-)
DBA/2J	MGP_DBA2J_G0025603	protein coding gene	Chr2:57130416-57163325 (-)
FVB/NJ	MGP_FVBNJ_G0025565	protein coding gene	Chr2:56679099-56712167 (-)
LP/J	MGP_LPJ_G0025691	protein coding gene	Chr2:59684775-59718923 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025596	protein coding gene	Chr2:65552544-65594067 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0026235	protein coding gene	Chr2:59133556-59175927 (-)
PWK/PhJ	MGP_PWKPhJ_G0024697	protein coding gene	Chr2:56984234-57016895 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0024504	protein coding gene	Chr2:59201355-59237178 (-)
WSB/EiJ	MGP_WSBEiJ_G0025024	protein coding gene	Chr2:59428732-59463808 (-)

Human Ortholog

CD302, CD302 molecule

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CD302, CD302 molecule
Synonyms

BIMLEC, CLEC13A, DCL-1, DCL1
Links

HGNC:30843

NCBI Gene ID: 9936

neXtProt AC: NX_Q8IX05

UniProt: Q8IX05
Chr Location

2q24.2; chr2:159768628-159798255 (-) GRCh38

MGI Vertebrate Homology

Cd302 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CD302
Gene Tree

Cd302

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Phenotype Summary

4 phenotypes from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

1
Endonuclease-mediated

1
Targeted

4
Genomic Mutations

1 involving Cd302
Find Mice (IMSR)

14 strains or lines available

Mice homozygous for a null allele exhibit reduced migratory dendritic cells.

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All GO Annotations

7
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

714
Tissues

4
cDNA Data

7
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

36
RefSeq

4
UniProt

1
CCDS

CCDS16058.1, CCDS71058.1

Ensembl

ENSMUSG00000060703 (Evidence)
NCBI Gene

66205

			Length	Strain/Species	Flank
genomic	66205	NCBI Gene Model \| MGI Sequence Detail	32492	C57BL/6J	± kb
transcript	NM_001290660	RefSeq \| MGI Sequence Detail	1363	C57BL/6
polypeptide	Q9DCG2	UniProt \| EBI \| MGI Sequence Detail	228	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000001305 CD302 molecule

(term hierarchy)
InterPro Domains

IPR050111 C-type lectin and snaclec domain-containing protein

IPR016187 C-type lectin fold

IPR001304 C-type lectin-like

IPR016186 C-type lectin-like/link domain superfamily
GlyGen

Q9DCG2 1 site, 1 N-linked glycan (1 site)

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All nucleic 7

cDNA 7

Microarray probesets 3

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MGI:2138845

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 4

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:301848 Lo TH, et al., Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016 Aug 1;197(3):885-98

TSS for Cd302:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr504	Chr2:60114684-60114689 (-)	141 bp
Tssr24197	Chr2:60114636-60114645 (-)	187 bp
Tssr503	Chr2:60114571-60114579 (-)	253 bp
Tssr24196	Chr2:60114553-60114562 (-)	270 bp
Tssr24195	Chr2:60114442-60114503 (-)	355 bp
Tssr24193	Chr2:60093891-60093909 (-)	20,928 bp
Tssr24192	Chr2:60083895-60083909 (-)	30,926 bp
Tssr24191	Chr2:60082837-60082838 (-)	31,990 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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