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Med7 Gene Detail
Summary
  • Symbol
    Med7
  • Name
    mediator complex subunit 7
  • Synonyms
    1110063B05Rik, Crsp33, Crsp9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913463
    NCBI Gene: 66213
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:46327752-46333548 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 27.88 cM, cytoband B1.2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913463
 protein coding gene Chr11:46327742-46333548 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018194
 protein coding gene Chr11:45356369-45362163 (+)
A/J MGP_AJ_G0018166
 protein coding gene Chr11:43613377-43619171 (+)
AKR/J MGP_AKRJ_G0018131
 protein coding gene Chr11:44874661-44880459 (+)
BALB/cJ MGP_BALBcJ_G0018135
 protein coding gene Chr11:43772970-43778933 (+)
C3H/HeJ MGP_C3HHeJ_G0017949
 protein coding gene Chr11:44910098-44915893 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018589
 protein coding gene Chr11:46707739-46713532 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016244
 protein coding gene Chr11:41590401-41596263 (+)
CAST/EiJ MGP_CASTEiJ_G0017512
 protein coding gene Chr11:45035379-45041201 (+)
CBA/J MGP_CBAJ_G0017921
 protein coding gene Chr11:48893708-48899503 (+)
DBA/2J MGP_DBA2J_G0018031
 protein coding gene Chr11:43358242-43364033 (+)
FVB/NJ MGP_FVBNJ_G0018025
 protein coding gene Chr11:43036075-43041868 (+)
LP/J MGP_LPJ_G0018103
 protein coding gene Chr11:45604406-45610201 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018049
 protein coding gene Chr11:50406078-50411869 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018628
 protein coding gene Chr11:45031024-45036820 (+)
PWK/PhJ MGP_PWKPhJ_G0017292
 protein coding gene Chr11:43445740-43451571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017085
 protein coding gene Chr11:44832182-44834338 (+)
WSB/EiJ MGP_WSBEiJ_G0017562
 protein coding gene Chr11:44724947-44730740 (+)



Homology
more
  • Human Ortholog
    MED7, mediator complex subunit 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MED7, mediator complex subunit 7
  • Synonyms
    ARC34, CRSP33, CRSP9
  • Links
    NCBI Gene ID: 9443
    neXtProt AC: NX_O43513
    UniProt: O43513

  • Chr Location
    5q33.3; chr5:157137424-157159019 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    831
  • Tissues
    113
  • cDNA Data
    56
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020397 Ensembl Gene Model | MGI Sequence Detail 5797 C57BL/6J ±  kb
transcript ENSMUST00000109232 Ensembl | MGI Sequence Detail 2547 Not Applicable  
polypeptide ENSMUSP00000104855 Ensembl | MGI Sequence Detail 233 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 56
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 10
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:347774 Kolonay DW, et al., Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. Front Cell Dev Biol. 2024;12:1331563
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory