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Eapp Gene Detail
Summary
  • Symbol
    Eapp
  • Name
    E2F-associated phosphoprotein
  • Synonyms
    1810011O16Rik, EAPP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913516
    NCBI Gene: 66266
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:54717125-54742682 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 23.46 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    645 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913516
 protein coding gene Chr12:54717125-54743245 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019737
 protein coding gene Chr12:53604241-53633044 (-)
A/J MGP_AJ_G0019699
 protein coding gene Chr12:51717511-51749836 (-)
AKR/J MGP_AKRJ_G0019670
 protein coding gene Chr12:53275841-53299322 (-)
BALB/cJ MGP_BALBcJ_G0019677
 protein coding gene Chr12:51990048-52014065 (-)
C3H/HeJ MGP_C3HHeJ_G0019480
 protein coding gene Chr12:53377302-53401369 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020125
 protein coding gene Chr12:55266095-55287095 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017748
 protein coding gene Chr12:49996937-50022246 (-)
CAST/EiJ MGP_CASTEiJ_G0019033
 protein coding gene Chr12:48399826-48428491 (-)
CBA/J MGP_CBAJ_G0019452
 protein coding gene Chr12:57143406-57174343 (-)
DBA/2J MGP_DBA2J_G0019566
 protein coding gene Chr12:51560818-51583322 (-)
FVB/NJ MGP_FVBNJ_G0019555
 protein coding gene Chr12:50988464-51011456 (-)
LP/J MGP_LPJ_G0019638
 protein coding gene Chr12:53672358-53701091 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019591
 protein coding gene Chr12:58745220-58768274 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020163
 protein coding gene Chr12:52756304-52780291 (-)
PWK/PhJ MGP_PWKPhJ_G0018800
 protein coding gene Chr12:46145442-46166579 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018594
 protein coding gene Chr12:47353626-47377184 (-)
WSB/EiJ MGP_WSBEiJ_G0019084
 protein coding gene Chr12:53250542-53273040 (-)



Homology
more
  • Human Ortholog
    EAPP, E2F associated phosphoprotein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EAPP, E2F associated phosphoprotein
  • Synonyms
    BM036, C14orf11
  • Links
    NCBI Gene ID: 55837
    neXtProt AC: NX_Q56P03
    UniProt: Q56P03

  • Chr Location
    14q13.1; chr14:34515938-34539704 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    29
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054302 Ensembl Gene Model | MGI Sequence Detail 25558 C57BL/6J ±  kb
transcript ENSMUST00000161592 Ensembl | MGI Sequence Detail 4186 Not Applicable  
polypeptide ENSMUSP00000123698 Ensembl | MGI Sequence Detail 281 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:100168 Novy M, et al., EAPP, a novel E2F binding protein that modulates E2F-dependent transcription. Mol Biol Cell. 2005 May;16(5):2181-90
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory