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Tpd52l2 Gene Detail
Summary
  • Symbol
    Tpd52l2
  • Name
    tumor protein D52-like 2
  • Synonyms
    2810411G23Rik, D54
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913564
    NCBI Gene: 66314
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181138935-181159759 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    335 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913564
 protein coding gene Chr2:181138935-181160103 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027026
 protein coding gene Chr2:188094724-188118661 (+)
A/J MGP_AJ_G0026992
 protein coding gene Chr2:180348141-180369052 (+)
AKR/J MGP_AKRJ_G0026962
 protein coding gene Chr2:185758374-185779339 (+)
BALB/cJ MGP_BALBcJ_G0027000
 protein coding gene Chr2:180827761-180848552 (+)
C3H/HeJ MGP_C3HHeJ_G0026742
 protein coding gene Chr2:186108515-186129324 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027446
 protein coding gene Chr2:193543092-193569296 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024810
 protein coding gene Chr2:171035367-171056096 (+)
CAST/EiJ MGP_CASTEiJ_G0026201
 protein coding gene Chr2:184372000-184394852 (+)
CBA/J MGP_CBAJ_G0026719
 protein coding gene Chr2:200542376-200563176 (+)
DBA/2J MGP_DBA2J_G0026856
 protein coding gene Chr2:179448086-179468856 (+)
FVB/NJ MGP_FVBNJ_G0026822
 protein coding gene Chr2:178064477-178086270 (+)
LP/J MGP_LPJ_G0026958
 protein coding gene Chr2:188119844-188140740 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026842
 protein coding gene Chr2:203106390-203128045 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027506
 protein coding gene Chr2:185725589-185746601 (+)
PWK/PhJ MGP_PWKPhJ_G0025937
 protein coding gene Chr2:176973153-176994054 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025737
 protein coding gene Chr2:182226370-182247187 (+)
WSB/EiJ MGP_WSBEiJ_G0026273
 protein coding gene Chr2:186712401-186733340 (+)



Homology
more
  • Human Ortholog
    TPD52L2, TPD52 like 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPD52L2, TPD52 like 2
  • Synonyms
    D54, TPD54
  • Links
    NCBI Gene ID: 7165
    neXtProt AC: NX_O43399
    UniProt: O43399

  • Chr Location
    20q13.33; chr20:63865228-63891545 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female mice homozygous for a knock-out allele exhibit decreased body length and absent or minimal hepatic lipidosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    19
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000000827 Ensembl Gene Model | MGI Sequence Detail 20825 C57BL/6J ±  kb
    transcript ENSMUST00000108799 Ensembl | MGI Sequence Detail 985 Not Applicable  
    polypeptide ENSMUSP00000104427 Ensembl | MGI Sequence Detail 229 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 19

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2139162, MGI:2139523
    References
    more
    • Summaries
      All 31
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory