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Atp6v1c1 Gene Detail
Summary
  • Symbol
    Atp6v1c1
  • Name
    ATPase, H+ transporting, lysosomal V1 subunit C1
  • Synonyms
    1700025B18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913585
    NCBI Gene: 66335
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:38662177-38692690 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 15.18 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    686 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913585
protein coding gene Chr15:38662096-38692690 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021809
protein coding gene Chr15:37199697-37231730 (+)
A/J MGP_AJ_G0021769
protein coding gene Chr15:35748230-35779755 (+)
AKR/J MGP_AKRJ_G0021750
protein coding gene Chr15:36823597-36856205 (+)
BALB/cJ MGP_BALBcJ_G0021776
protein coding gene Chr15:35797244-35827682 (+)
C3H/HeJ MGP_C3HHeJ_G0021550
protein coding gene Chr15:36758718-36790156 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022215
protein coding gene Chr15:38629338-38661807 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019752
protein coding gene Chr15:33524959-33556016 (+)
CAST/EiJ MGP_CASTEiJ_G0021067
protein coding gene Chr15:37187931-37218281 (+)
CBA/J MGP_CBAJ_G0021519
protein coding gene Chr15:39865860-39900559 (+)
DBA/2J MGP_DBA2J_G0021643
protein coding gene Chr15:35589921-35620997 (+)
FVB/NJ MGP_FVBNJ_G0021621
protein coding gene Chr15:35001151-35031640 (+)
LP/J MGP_LPJ_G0021713
protein coding gene Chr15:37061610-37095552 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0022238
protein coding gene Chr15:36957701-36989292 (+)
PWK/PhJ MGP_PWKPhJ_G0020812
protein coding gene Chr15:35651317-35683539 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020649
protein coding gene Chr15:36653746-36683826 (+)
WSB/EiJ MGP_WSBEiJ_G0021122
protein coding gene Chr15:36905410-36937062 (+)



Homology
more
  • Human Ortholog
    ATP6V1C1, ATPase H+ transporting V1 subunit C1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP6V1C1, ATPase H+ transporting V1 subunit C1
  • Synonyms
    ATP6C, ATP6D, VATC, Vma5
  • Links
    NCBI Gene ID: 528
    neXtProt AC: NX_P21283
    UniProt: P21283

  • Chr Location
    8q22.3; chr8:103021063-103073051 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022295 Ensembl Gene Model | MGI Sequence Detail 30514 C57BL/6J ±  kb
transcript ENSMUST00000022904 Ensembl | MGI Sequence Detail 2071 Not Applicable  
polypeptide ENSMUSP00000022904 Ensembl | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2146327
References
more
  • Summaries
    All 48
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory