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Ostc Gene Detail
Summary
  • Symbol
    Ostc
  • Name
    oligosaccharyltransferase complex subunit (non-catalytic)
  • Synonyms
    2310008M10Rik, 5730557H03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913607
    NCBI Gene: 66357
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:130489566-130503093 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 60.53 cM, cytoband H1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    496 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913607
 protein coding gene Chr3:130489561-130503093 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027882
 protein coding gene Chr3:133444801-133458411 (-)
A/J MGP_AJ_G0027840
 protein coding gene Chr3:128762755-128776325 (-)
AKR/J MGP_AKRJ_G0027805
 protein coding gene Chr3:132107013-132120586 (-)
BALB/cJ MGP_BALBcJ_G0027853
 protein coding gene Chr3:128615234-128632093 (-)
C3H/HeJ MGP_C3HHeJ_G0027582
 protein coding gene Chr3:132506302-132520480 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028297
 protein coding gene Chr3:138171110-138184680 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025635
 protein coding gene Chr3:124284319-124297062 (-)
CAST/EiJ MGP_CASTEiJ_G0027039
 protein coding gene Chr3:132206620-132220124 (-)
CBA/J MGP_CBAJ_G0027558
 protein coding gene Chr3:142812418-142826181 (-)
DBA/2J MGP_DBA2J_G0027699
 protein coding gene Chr3:127967017-127980636 (-)
FVB/NJ MGP_FVBNJ_G0027666
 protein coding gene Chr3:125546271-125559871 (-)
LP/J MGP_LPJ_G0027808
 protein coding gene Chr3:134923607-134938433 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027697
 protein coding gene Chr3:150763118-150776697 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028354
 protein coding gene Chr3:131779017-131792590 (-)
PWK/PhJ MGP_PWKPhJ_G0026763
 protein coding gene Chr3:127698055-127711698 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026588
 protein coding gene Chr3:129834552-129847314 (-)
WSB/EiJ MGP_WSBEiJ_G0027118
 protein coding gene Chr3:132504667-132518211 (-)



Homology
more
  • Human Ortholog
    OSTC, oligosaccharyltransferase complex non-catalytic subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSTC, oligosaccharyltransferase complex non-catalytic subunit
  • Synonyms
    DC2
  • Links
    NCBI Gene ID: 58505
    neXtProt AC: NX_Q9NRP0
    UniProt: Q9NRP0

  • Chr Location
    4q25; chr4:108650585-108667820 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    8
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Ostc
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    762
  • Tissues
    15
  • cDNA Data
    127
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66357 NCBI Gene Model | MGI Sequence Detail 13528 C57BL/6J ±  kb
transcript NM_025509 RefSeq | MGI Sequence Detail 1081 C57BL/6  
polypeptide Q78XF5 UniProt | EBI | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000012066 oligosaccharyltransferase complex subunit OSTC
    (term hierarchy)
  • InterPro Domains
    IPR021149 Oligosaccharyl transferase complex, subunit OST3/OST6
    IPR042416 Oligosaccharyltransferase complex subunit OSTC
  • GlyGen
    Q78XF5 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 128
    cDNA 128

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917910
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:319945 Ramirez AS, et al., Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B. Science. 2019 Dec 13;366(6471):1372-1375
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory