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Ppp1r7 Gene Detail
Summary
  • Symbol
    Ppp1r7
  • Name
    protein phosphatase 1, regulatory subunit 7
  • Synonyms
    2310014J01Rik, SDS22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913635
    NCBI Gene: 66385
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:93271350-93295344 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 47.24 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    579 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913635
 protein coding gene Chr1:93270576-93301211 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016340
 protein coding gene Chr1:94961804-94994886 (+)
A/J MGP_AJ_G0016321
 protein coding gene Chr1:91560784-91591335 (+)
AKR/J MGP_AKRJ_G0016282
 protein coding gene Chr1:94261589-94292013 (+)
BALB/cJ MGP_BALBcJ_G0016277
 protein coding gene Chr1:91742195-91772716 (+)
C3H/HeJ MGP_C3HHeJ_G0016106
 protein coding gene Chr1:94516199-94548594 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016736
 protein coding gene Chr1:98579352-98611579 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014454
 protein coding gene Chr1:85816697-85847565 (+)
CAST/EiJ MGP_CASTEiJ_G0015689
 protein coding gene Chr1:93849902-93881586 (+)
CBA/J MGP_CBAJ_G0016080
 protein coding gene Chr1:101771746-101803956 (+)
DBA/2J MGP_DBA2J_G0016185
 protein coding gene Chr1:90755978-90786671 (+)
FVB/NJ MGP_FVBNJ_G0016184
 protein coding gene Chr1:89830705-89861759 (+)
LP/J MGP_LPJ_G0016256
 protein coding gene Chr1:96139523-96171115 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016209
 protein coding gene Chr1:104874624-104906080 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016775
 protein coding gene Chr1:94278468-94309561 (+)
PWK/PhJ MGP_PWKPhJ_G0015474
 protein coding gene Chr1:90194500-90226124 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015258
 protein coding gene Chr1:93233643-93265328 (+)
WSB/EiJ MGP_WSBEiJ_G0015749
 protein coding gene Chr1:94100051-94131549 (+)



Homology
more
  • Human Ortholog
    PPP1R7, protein phosphatase 1 regulatory subunit 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R7, protein phosphatase 1 regulatory subunit 7
  • Synonyms
    SDS22
  • Links
    NCBI Gene ID: 5510
    neXtProt AC: NX_Q15435
    UniProt: Q15435

  • Chr Location
    2q37.3; chr2:241149573-241183652 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    133
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66385 NCBI Gene Model | MGI Sequence Detail 23995 C57BL/6J ±  kb
transcript NM_023200 RefSeq | MGI Sequence Detail 3668 C57BL/6  
polypeptide Q3UM45 UniProt | EBI | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013130 protein phosphatase 1 regulatory subunit 7
    (term hierarchy)
  • InterPro Domains
    IPR050576 Ciliary and flagellar integrity-associated protein
    IPR001611 Leucine-rich repeat
    IPR025875 Leucine rich repeat 4
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
    IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
  • GlyGen
    Q3UM45 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 133
    cDNA 133

    Microarray probesets 5
References
more
  • Summaries
    All 40
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:248457 Chiang DY, et al., Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients. J Am Coll Cardiol. 2015 Jan 20;65(2):163-73
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory