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Chchd7 Gene Detail
Summary
  • Symbol
    Chchd7
  • Name
    coiled-coil-helix-coiled-coil-helix domain containing 7
  • Synonyms
    1810049H20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913683
    NCBI Gene: 66433
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:3938888-3951046 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 2.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913683
 protein coding gene Chr4:3938847-3951382 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028027
 protein coding gene Chr4:429743-441872 (+)
A/J MGP_AJ_G0027985
 protein coding gene Chr4:503600-515742 (+)
AKR/J MGP_AKRJ_G0027951
 protein coding gene Chr4:440828-452974 (+)
BALB/cJ MGP_BALBcJ_G0027997
 protein coding gene Chr4:469991-482136 (+)
C3H/HeJ MGP_C3HHeJ_G0027727
 protein coding gene Chr4:601176-613306 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028440
 protein coding gene Chr4:595137-607270 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025784
 protein coding gene Chr4:443547-455987 (+)
CAST/EiJ MGP_CASTEiJ_G0027180
 protein coding gene Chr4:515212-527355 (+)
CBA/J MGP_CBAJ_G0027702
 protein coding gene Chr4:470232-482384 (+)
DBA/2J MGP_DBA2J_G0027842
 protein coding gene Chr4:467658-479792 (+)
FVB/NJ MGP_FVBNJ_G0027809
 protein coding gene Chr4:397009-409519 (+)
LP/J MGP_LPJ_G0027953
 protein coding gene Chr4:478234-490375 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027842
 protein coding gene Chr4:652015-664164 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028499
 protein coding gene Chr4:437023-449175 (+)
PWK/PhJ MGP_PWKPhJ_G0026902
 protein coding gene Chr4:533371-545843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026732
 protein coding gene Chr4:466669-478915 (+)
WSB/EiJ MGP_WSBEiJ_G0027260
 protein coding gene Chr4:583650-595808 (+)



Homology
more
  • Human Ortholog
    CHCHD7, coiled-coil-helix-coiled-coil-helix domain containing 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHCHD7, coiled-coil-helix-coiled-coil-helix domain containing 7
  • Synonyms
    COX23
  • Links
    NCBI Gene ID: 79145
    neXtProt AC: NX_Q9BUK0
    UniProt: Q9BUK0

  • Chr Location
    8q12.1; chr8:56211686-56218809 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    61
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042198 Ensembl Gene Model | MGI Sequence Detail 12159 C57BL/6J ±  kb
    transcript ENSMUST00000121651 Ensembl | MGI Sequence Detail 620 Not Applicable  
    polypeptide ENSMUSP00000112967 Ensembl | MGI Sequence Detail 85 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000030528 coiled-coil-helix-coiled-coil-helix domain-containing protein 7
      (term hierarchy)
    • InterPro Domains
      IPR009069 Cysteine alpha-hairpin motif superfamily
      IPR051040 Cytochrome c oxidase-assembly factor COX23
      IPR048280 Cytochrome oxidase c subunit VIb-like
    Molecular
    Reagents
    less
    • All nucleic 62
      cDNA 62

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory