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Mgst3 Gene Detail
Summary
  • Symbol
    Mgst3
  • Name
    microsomal glutathione S-transferase 3
  • Synonyms
    2010012L10Rik, 2010306B17Rik, 2700004G04Rik, GST-III
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913697
    NCBI Gene: 66447
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
  • Candidate for QTL
    3 QTL
Location &
Maps
more
  • Sequence Map
    Chr1:167199535-167221410 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 74.76 cM, cytoband H2
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    797 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913697
 protein coding gene Chr1:167199535-167221410 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016714
 protein coding gene Chr1:172936369-172961758 (-)
A/J MGP_AJ_G0016694
 protein coding gene Chr1:165885855-165907723 (-)
AKR/J MGP_AKRJ_G0016660
 protein coding gene Chr1:170897599-170920333 (-)
BALB/cJ MGP_BALBcJ_G0016655
 protein coding gene Chr1:166367857-166391184 (-)
C3H/HeJ MGP_C3HHeJ_G0016479
 protein coding gene Chr1:171128309-171153322 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017116
 protein coding gene Chr1:178728567-178750255 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014825
 protein coding gene Chr1:157727696-157749524 (-)
CAST/EiJ MGP_CASTEiJ_G0016059
 protein coding gene Chr1:170736717-170760356 (-)
CBA/J MGP_CBAJ_G0016454
 protein coding gene Chr1:185068240-185090148 (-)
DBA/2J MGP_DBA2J_G0016560
 protein coding gene Chr1:164728580-164750503 (-)
FVB/NJ MGP_FVBNJ_G0016558
 protein coding gene Chr1:163175843-163197967 (-)
LP/J MGP_LPJ_G0016631
 protein coding gene Chr1:174009963-174031968 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016583
 protein coding gene Chr1:192469557-192493997 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017153
 protein coding gene Chr1:170766944-170788840 (-)
PWK/PhJ MGP_PWKPhJ_G0015845
 protein coding gene Chr1:163933059-163955262 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015631
 protein coding gene Chr1:169542275-169565742 (-)
WSB/EiJ MGP_WSBEiJ_G0016121
 protein coding gene Chr1:170862117-170884025 (-)



Homology
more
  • Human Ortholog
    MGST3, microsomal glutathione S-transferase 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MGST3, microsomal glutathione S-transferase 3
  • Synonyms
    GST-3, GST-III
  • Links
    NCBI Gene ID: 4259
    neXtProt AC: NX_O14880
    UniProt: O14880

  • Chr Location
    1q24.1; chr1:165631213-165661796 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    939
  • Tissues
    125
  • cDNA Data
    165
  • Literature Summary
    10
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66447 NCBI Gene Model | MGI Sequence Detail 21876 C57BL/6J ±  kb
transcript NM_025569 RefSeq | MGI Sequence Detail 1097 C57BL/6  
polypeptide Q9CPU4 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000010392 glutathione S-transferase 3, mitochondrial
    (term hierarchy)
  • EC
    1.11.1.-, 2.5.1.-, 4.4.1.20
  • InterPro Domains
    IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily
    IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein
    IPR050997 Membrane-associated proteins in eicosanoid and glutathione metabolism
  • GlyGen
    Q9CPU4 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 167
    cDNA 165
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915449, MGI:1922953, MGI:2138101
References
more
  • Summaries
    All 55
    Developmental Gene Expression 10
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory