Rps23 MGI Mouse Gene Detail - MGI:1913725

Symbol

Rps23
Name

ribosomal protein S23
Synonyms

2410044J15Rik

Feature Type

protein coding gene
IDs

MGI:1913725
NCBI Gene: 66475
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr13:91071241-91072851 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 46.46 cM, cytoband C3
Mapping Data

2 experiments

SNPs within 2kb

259 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913725	protein coding gene	Chr13:91071077-91073069 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020805	protein coding gene	Chr13:92149214-92151025 (+)
A/J	MGP_AJ_G0020759	protein coding gene	Chr13:88750481-88752594 (+)
AKR/J	MGP_AKRJ_G0020732	protein coding gene	Chr13:91457956-91460347 (+)
BALB/cJ	MGP_BALBcJ_G0020755	protein coding gene	Chr13:89407506-89409325 (+)
C3H/HeJ	MGP_C3HHeJ_G0020549	protein coding gene	Chr13:91146372-91148165 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021192	protein coding gene	Chr13:95016032-95018793 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018760	protein coding gene	Chr13:84755955-84757761 (+)
CAST/EiJ	MGP_CASTEiJ_G0020067	protein coding gene	Chr13:90373788-90375597 (+)
CBA/J	MGP_CBAJ_G0020508	protein coding gene	Chr13:98773043-98774862 (+)
DBA/2J	MGP_DBA2J_G0020633	protein coding gene	Chr13:88536587-88538427 (+)
FVB/NJ	MGP_FVBNJ_G0020613	protein coding gene	Chr13:87356996-87358910 (+)
LP/J	MGP_LPJ_G0020706	protein coding gene	Chr13:92300043-92303478 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020642	protein coding gene	Chr13:99247037-99249650 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021232	protein coding gene	Chr13:90862026-90863865 (+)
PWK/PhJ	MGP_PWKPhJ_G0019820	protein coding gene	Chr13:87263424-87265835 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019643	protein coding gene	Chr13:87132251-87134276 (+)
WSB/EiJ	MGP_WSBEiJ_G0020125	protein coding gene	Chr13:91334012-91335831 (+)

Human Ortholog

RPS23, ribosomal protein S23

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPS23, ribosomal protein S23
Synonyms

BTDD, MABAS, MCINS, PAMAS, S23, uS12
Links

HGNC:10410

NCBI Gene ID: 6228

neXtProt AC: NX_P62266

UniProt: P62266
Chr Location

5q14.2; chr5:82273320-82278396 (-) GRCh38

MGI Vertebrate Homology

Rps23 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPS23
Protein SuperFamily

Ribosomal_S12/S23
Gene Tree

Rps23

Diseases

1 with human RPS23 associations

				Human Disease	Mouse Models
				brachycephaly, trichomegaly, and developmental delay IDs brachycephaly, trichomegaly, and developmental delay DOID:0070415 OMIM:617412

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

14
Chemically induced (other)

1
Gene trapped

12
Targeted

1
Genomic Mutations

1 involving Rps23
Find Mice (IMSR)

17 strains or lines available

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All GO Annotations

37
GO References

10

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

246
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rps23

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All Sequences

52
RefSeq

2
UniProt

5
CCDS

CCDS26674.1

Ensembl

ENSMUSG00000049517 (Evidence)
NCBI Gene

66475

			Length	Strain/Species	Flank
genomic	66475	NCBI Gene Model \| MGI Sequence Detail	1611	C57BL/6J	± kb
transcript	NM_024175	RefSeq \| MGI Sequence Detail	572	C57BL/6
polypeptide	P62267	UniProt \| EBI \| MGI Sequence Detail	143	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000014266 eukaryotic-type small ribosomal subunit protein uS12

(term hierarchy)
PDB

7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR012340 Nucleic acid-binding, OB-fold

IPR006032 Small ribosomal subunit protein uS12

IPR005680 Small ribosomal subunit protein uS12, eukaryotic/archaeal
GlyGen

P62267 1 site, 1 O-linked glycan (1 site)

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All nucleic 247

Genomic 1

cDNA 246

Microarray probesets 5

Summaries

All 38

Developmental Gene Expression 1

Gene Ontology 10

Phenotypes 8
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rps23:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120595	Chr13:91071241-91071289 (+)	24 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24