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Ndufb3 Gene Detail
Summary
  • Symbol
    Ndufb3
  • Name
    NADH:ubiquinone oxidoreductase subunit B3
  • Synonyms
    2700033I16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913745
    NCBI Gene: 66495
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:58625556-58635123 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 29.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    276 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913745
 protein coding gene Chr1:58625543-58635123 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016055
 protein coding gene Chr1:58472713-58481951 (+)
A/J MGP_AJ_G0016038
 protein coding gene Chr1:56418782-56428152 (+)
AKR/J MGP_AKRJ_G0015994
 protein coding gene Chr1:57941872-57952282 (+)
BALB/cJ MGP_BALBcJ_G0015993
 protein coding gene Chr1:56448473-56459183 (+)
C3H/HeJ MGP_C3HHeJ_G0015825
 protein coding gene Chr1:58207360-58217698 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016446
 protein coding gene Chr1:60804087-60814615 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014168
 protein coding gene Chr1:52349916-52359154 (+)
CAST/EiJ MGP_CASTEiJ_G0015407
 protein coding gene Chr1:57455111-57464380 (+)
CBA/J MGP_CBAJ_G0015797
 protein coding gene Chr1:62598635-62607886 (+)
DBA/2J MGP_DBA2J_G0015898
 protein coding gene Chr1:55811252-55820391 (+)
FVB/NJ MGP_FVBNJ_G0015900
 protein coding gene Chr1:55152590-55162380 (+)
LP/J MGP_LPJ_G0015970
 protein coding gene Chr1:59358144-59367361 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015920
 protein coding gene Chr1:65598091-65608899 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016493
 protein coding gene Chr1:57913335-57922585 (+)
PWK/PhJ MGP_PWKPhJ_G0015194
 protein coding gene Chr1:55212672-55222524 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014974
 protein coding gene Chr1:57505712-57514953 (+)
WSB/EiJ MGP_WSBEiJ_G0015470
 protein coding gene Chr1:57604475-57615456 (+)



Homology
more
  • Human Ortholog
    NDUFB3, NADH:ubiquinone oxidoreductase subunit B3
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFB3, NADH:ubiquinone oxidoreductase subunit B3
  • Synonyms
    B12, CI-B12, MC1DN25
  • Links
    NCBI Gene ID: 4709
    neXtProt AC: NX_O43676
    UniProt: O43676

  • Chr Location
    2q33.1; chr2:201071433-201085750 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NDUFB3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ndufb3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    92
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66495 NCBI Gene Model | MGI Sequence Detail 9568 C57BL/6J ±  kb
transcript NM_025597 RefSeq | MGI Sequence Detail 769 C57BL/6  
polypeptide Q9CQZ6 UniProt | EBI | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 92
    cDNA 92

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144808
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory