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Bpifb2 Gene Detail
Summary
  • Symbol
    Bpifb2
  • Name
    BPI fold containing family B, member 2
  • Synonyms
    2310034L21Rik, 2310069A01Rik, Bpil1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913807
    NCBI Gene: 66557
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:153716965-153737190 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    873 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913807
 protein coding gene Chr2:153716925-153737190 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026700
 protein coding gene Chr2:158580743-158604436 (+)
A/J MGP_AJ_G0026666
 protein coding gene Chr2:152195953-152216065 (+)
AKR/J MGP_AKRJ_G0026637
 protein coding gene Chr2:156673570-156694854 (+)
BALB/cJ MGP_BALBcJ_G0026676
 protein coding gene Chr2:152534043-152553671 (+)
C3H/HeJ MGP_C3HHeJ_G0026418
 protein coding gene Chr2:157051492-157071491 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027125
 protein coding gene Chr2:163205814-163229818 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024495
 protein coding gene Chr2:145771104-145789750 (+)
CAST/EiJ MGP_CASTEiJ_G0025879
 protein coding gene Chr2:157319934-157339773 (+)
CBA/J MGP_CBAJ_G0026397
 protein coding gene Chr2:169207679-169227937 (+)
DBA/2J MGP_DBA2J_G0026532
 protein coding gene Chr2:151425461-151442336 (+)
FVB/NJ MGP_FVBNJ_G0026498
 protein coding gene Chr2:149872203-149890796 (+)
LP/J MGP_LPJ_G0026637
 protein coding gene Chr2:158704051-158723153 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026520
 protein coding gene Chr2:173190171-173209228 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027180
 protein coding gene Chr2:156566021-156586249 (+)
PWK/PhJ MGP_PWKPhJ_G0025613
 protein coding gene Chr2:150952177-150972266 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025416
 protein coding gene Chr2:155422766-155443777 (+)
WSB/EiJ MGP_WSBEiJ_G0025949
 protein coding gene Chr2:157475532-157494718 (+)



Homology
more
  • Human Ortholog
    BPIFB2, BPI fold containing family B member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BPIFB2, BPI fold containing family B member 2
  • Synonyms
    BPIL1, C20orf184, dJ726C3.2, LPLUNC2, RYSR
  • Links
    NCBI Gene ID: 80341
    neXtProt AC: NX_Q8N4F0
    UniProt: Q8N4F0

  • Chr Location
    20q11.21
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    21
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027481 Ensembl Gene Model | MGI Sequence Detail 20226 C57BL/6J ±  kb
transcript ENSMUST00000028983 Ensembl | MGI Sequence Detail 1730 Not Applicable  
polypeptide ENSMUSP00000028983 Ensembl | MGI Sequence Detail 462 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004795 BPI fold-containing family B member 2
    (term hierarchy)
  • InterPro Domains
    IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
    IPR051660 BPI fold-containing BPI/LBP
    IPR001124 Lipid-binding serum glycoprotein, C-terminal
    IPR017942 Lipid-binding serum glycoprotein, N-terminal
  • GlyGen
    Q8C1E1 3 sites
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 4
Other
Accession IDs
less
MGI:1917437, MGI:2139250
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:174122 Bingle CD, et al., Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Biochem Soc Trans. 2011 Aug 1;39(4):977-83
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory