Rdm1 Gene Detail

Summary

• Symbol
  Rdm1
• Name
  RAD52 motif 1
• Synonyms
  2410008M22Rik, Rad52b

• Feature Type
  protein coding gene
• IDs
  MGI:1913849
  NCBI Gene: 66599
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr11:101518021-101526926 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 65.48 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  447 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913849	protein coding gene	Chr11:101517992-101526926 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0019209	protein coding gene	Chr11:104524106-104536426 (+)
A/J	MGP_AJ_G0019177	protein coding gene	Chr11:100120921-100130601 (+)
AKR/J	MGP_AKRJ_G0019146	protein coding gene	Chr11:103231945-103240762 (+)
BALB/cJ	MGP_BALBcJ_G0019151	protein coding gene	Chr11:100610965-100620322 (+)
C3H/HeJ	MGP_C3HHeJ_G0018960	protein coding gene	Chr11:103414570-103423606 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0019600	protein coding gene	Chr11:107791721-107803399 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0017226	protein coding gene	Chr11:97566205-97573543 (+)
CAST/EiJ	MGP_CASTEiJ_G0018514	protein coding gene	Chr11:104386334-104397627 (+)
CBA/J	MGP_CBAJ_G0018929	protein coding gene	Chr11:112221277-112232148 (+)
DBA/2J	MGP_DBA2J_G0019041	protein coding gene	Chr11:99644663-99653792 (+)
FVB/NJ	MGP_FVBNJ_G0019031	protein coding gene	Chr11:99177555-99188540 (+)
LP/J	MGP_LPJ_G0019110	protein coding gene	Chr11:105060307-105069714 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0019062	protein coding gene	Chr11:111795063-111803974 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0019638	protein coding gene	Chr11:103562099-103574596 (+)
PWK/PhJ	MGP_PWKPhJ_G0018277	protein coding gene	Chr11:100701977-100711326 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0018069	protein coding gene	Chr11:103303891-103313517 (+)
WSB/EiJ	MGP_WSBEiJ_G0018563	protein coding gene	Chr11:103558041-103566927 (+)

Homology

• Human Ortholog
  RDM1, RAD52 motif containing 1

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  RDM1, RAD52 motif containing 1
  
• Synonyms
  RAD52B
• Links
  HGNC:19950

  NCBI Gene ID: 201299

  neXtProt AC: NX_Q8NG50

  UniProt: Q8NG50

  
  
• Chr Location
  17q12; chr17:35918066-35930773 (-)  GRCh38

---

• MGI Vertebrate Homology
  Rdm1 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: RDM1
• Gene Tree
  Rdm1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  14
• Gene trapped
  13
• Targeted
  1
• Genomic Mutations
  1 involving Rdm1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  27 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  9
• GO References
  4

Expression

• Assay Results
  755
• Tissues
  25
• cDNA Data
  60
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase rdm1
  ZFIN rdm1

Sequences &
Gene Models

• All Sequences
  44
• RefSeq
  8
• UniProt
  2
• CCDS
  CCDS25477.1

• Ensembl
  ENSMUSG00000010362 (Evidence)
• NCBI Gene
  66599

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000010362	Ensembl Gene Model | MGI Sequence Detail	8906	C57BL/6J
transcript	ENSMUST00000010506	Ensembl | MGI Sequence Detail	1124	Not Applicable
polypeptide	ENSMUSP00000010506	Ensembl | MGI Sequence Detail	281	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000013857 RAD52 motif-containing protein 1
  (term hierarchy)
• InterPro Domains
  IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
  IPR041247 Rad52 family
  IPR040224 RAD52 motif-containing protein 1
  IPR034200 RDM1, RNA recognition motif
  IPR035979 RNA-binding domain superfamily
  IPR000504 RNA recognition motif domain

Molecular
Reagents

• All nucleic 61

  cDNA 60

  Primer pair 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2144510

References

• Summaries
  All 37

  Developmental Gene Expression 2

  Gene Ontology 4

  Phenotypes 9
• Earliest
  J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
• Latest
  J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25

TSS for Rdm1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr105153	Chr11:101518769-101518798 (+)	763 bp