Golph3 MGI Mouse Gene Detail - MGI:1913879

Symbol

Golph3
Name

golgi phosphoprotein 3
Synonyms

4733401N08Rik, 5730410D03Rik

Feature Type

protein coding gene
IDs

MGI:1913879
NCBI Gene: 66629
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr15:12321536-12351677 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 5.90 cM
Mapping Data

2 experiments

SNPs within 2kb

620 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913879	protein coding gene	Chr15:12319617-12351687 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0021737	protein coding gene	Chr15:9556334-9589358 (+)
A/J	MGP_AJ_G0021697	protein coding gene	Chr15:9253341-9283151 (+)
AKR/J	MGP_AKRJ_G0021675	protein coding gene	Chr15:9508367-9538117 (+)
BALB/cJ	MGP_BALBcJ_G0021704	protein coding gene	Chr15:9160398-9190356 (+)
C3H/HeJ	MGP_C3HHeJ_G0021480	protein coding gene	Chr15:9461541-9492533 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0022143	protein coding gene	Chr15:9905362-9935131 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019684	protein coding gene	Chr15:8782220-8812031 (+)
CAST/EiJ	MGP_CASTEiJ_G0020996	protein coding gene	Chr15:9561155-9594162 (+)
CBA/J	MGP_CBAJ_G0021449	protein coding gene	Chr15:10187770-10222851 (+)
DBA/2J	MGP_DBA2J_G0021573	protein coding gene	Chr15:9108656-9138399 (+)
FVB/NJ	MGP_FVBNJ_G0021551	protein coding gene	Chr15:8958998-8989849 (+)
LP/J	MGP_LPJ_G0021641	protein coding gene	Chr15:9480422-9510149 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021576	protein coding gene	Chr15:10428093-10457826 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022166	protein coding gene	Chr15:9513548-9545526 (+)
PWK/PhJ	MGP_PWKPhJ_G0020739	protein coding gene	Chr15:9294823-9325748 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0020577	protein coding gene	Chr15:9436522-9475693 (+)
WSB/EiJ	MGP_WSBEiJ_G0021052	protein coding gene	Chr15:9495496-9526800 (+)

Human Ortholog

GOLPH3, golgi phosphoprotein 3

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GOLPH3, golgi phosphoprotein 3
Synonyms

GOPP1, GPP34, MIDAS, Vps74
Links

HGNC:15452

NCBI Gene ID: 64083

neXtProt AC: NX_Q9H4A6

UniProt: Q9H4A6
Chr Location

5p13.3; chr5:32124716-32174319 (-) GRCh38

MGI Vertebrate Homology

Golph3 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: GOLPH3
Gene Tree

Golph3

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Phenotype Summary

16 phenotypes from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Endonuclease-mediated

5
Gene trapped

3
Targeted

2
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

15 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

71
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

716
Tissues

9
cDNA Data

18
Literature Summary

3

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase golph3

ZFIN golph3a

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All Sequences

58
RefSeq

4
UniProt

4
CCDS

CCDS27389.1

Ensembl

ENSMUSG00000022200 (Evidence)
NCBI Gene

66629

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022200	Ensembl Gene Model \| MGI Sequence Detail	30142	C57BL/6J	± kb
transcript	ENSMUST00000059680	Ensembl \| MGI Sequence Detail	2652	Not Applicable
polypeptide	ENSMUSP00000057375	Ensembl \| MGI Sequence Detail	298	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000008142 Golgi phosphoprotein 3

(term hierarchy)
InterPro Domains

IPR008628 Golgi phosphoprotein 3-like

IPR038261 Golgi phosphoprotein 3-like domain superfamily

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All nucleic 20

cDNA 19

Primer pair 1

Microarray probesets 6

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MGI:1913947, MGI:2146213

Summaries

All 43

Developmental Gene Expression 3

Gene Ontology 8

Phenotypes 11
Earliest

J:38063 Sowden JC, et al., The identification of novel sequences expressed in the mouse notochord. Mamm Genome. 1997 Jan;8(1):42-4
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Golph3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr130734	Chr15:12321511-12321546 (+)	-7 bp
Tssr130735	Chr15:12321558-12321577 (+)	32 bp
Tssr130736	Chr15:12321595-12321606 (+)	65 bp
Tssr130737	Chr15:12321620-12321633 (+)	91 bp
Tssr130738	Chr15:12321702-12321711 (+)	171 bp
Tssr130739	Chr15:12350026-12350056 (+)	28,505 bp
Tssr130740	Chr15:12350165-12350177 (+)	28,635 bp
Tssr130741	Chr15:12350264-12350277 (+)	28,735 bp
Tssr130742	Chr15:12350303-12350323 (+)	28,777 bp
Tssr130743	Chr15:12350742-12350762 (+)	29,216 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24