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Nsa2 Gene Detail
Summary
  • Symbol
    Nsa2
  • Name
    NSA2 ribosome biogenesis homolog
  • Synonyms
    5730427N09Rik, LNR42, Nsa2p, Yr29
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913883
    NCBI Gene: 59050
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:97265935-97274434 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 50.66 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    336 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913883
 protein coding gene Chr13:97265932-97274445 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020857
 protein coding gene Chr13:98726267-98734535 (-)
A/J MGP_AJ_G0020811
 protein coding gene Chr13:94991241-95000500 (-)
AKR/J MGP_AKRJ_G0020785
 protein coding gene Chr13:97883040-97893272 (-)
BALB/cJ MGP_BALBcJ_G0020808
 protein coding gene Chr13:95675881-95684221 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0021243
 protein coding gene Chr13:101703404-101712605 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018813
 protein coding gene Chr13:90754690-90762793 (-)
CAST/EiJ MGP_CASTEiJ_G0020119
 protein coding gene Chr13:96919159-96928625 (-)
CBA/J MGP_CBAJ_G0020560
 protein coding gene Chr13:105762838-105773657 (-)
DBA/2J MGP_DBA2J_G0020685
 protein coding gene Chr13:94744416-94753059 (-)
FVB/NJ MGP_FVBNJ_G0020666
 protein coding gene Chr13:93511778-93520432 (-)
LP/J MGP_LPJ_G0020760
 protein coding gene Chr13:98834313-98844309 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020694
 protein coding gene Chr13:106108514-106116759 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021284
 protein coding gene Chr13:97306968-97317918 (-)
PWK/PhJ MGP_PWKPhJ_G0019871
 protein coding gene Chr13:93524215-93533096 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019695
 protein coding gene Chr13:93589388-93599782 (-)
WSB/EiJ MGP_WSBEiJ_G0020176
 protein coding gene Chr13:97761530-97771918 (-)



Homology
more
  • Human Ortholog
    NSA2, NSA2 ribosome biogenesis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NSA2, NSA2 ribosome biogenesis factor
  • Synonyms
    CDK105, HCL-G1, HCLG1, HUSSY-29, HUSSY29, TINP1
  • Links
    NCBI Gene ID: 10412
    neXtProt AC: NX_O95478
    UniProt: O95478

  • Chr Location
    5q13.3; chr5:74766991-74780113 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    15
  • cDNA Data
    19
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59050 NCBI Gene Model | MGI Sequence Detail 8500 C57BL/6J ±  kb
    transcript NM_021552 RefSeq | MGI Sequence Detail 2686 C57BL/6  
    polypeptide Q9CR47 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 21

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1926221
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:28008 Harrison SM, et al., Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Development. 1995 Aug;121(8):2479-89
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory