Tmem41a MGI Mouse Gene Detail - MGI:1913914

Symbol

Tmem41a
Name

transmembrane protein 41a
Synonyms

2900010K02Rik, 5730578N08Rik

Feature Type

protein coding gene
IDs

MGI:1913914
NCBI Gene: 66664
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr16:21753077-21766302 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 12.94 cM, cytoband B1
Mapping Data

2 experiments

SNPs within 2kb

270 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913914	protein coding gene	Chr16:21753076-21766302 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022663	protein coding gene	Chr16:19394932-19403865 (-)
A/J	MGP_AJ_G0022625	protein coding gene	Chr16:18458137-18468560 (-)
AKR/J	MGP_AKRJ_G0022600	protein coding gene	Chr16:19230500-19237753 (-)
BALB/cJ	MGP_BALBcJ_G0022629	protein coding gene	Chr16:18656674-18664287 (-)
C3H/HeJ	MGP_C3HHeJ_G0022394	protein coding gene	Chr16:19333335-19340441 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023080	protein coding gene	Chr16:19797140-19804105 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020598	protein coding gene	Chr16:19161718-19168720 (-)
CAST/EiJ	MGP_CASTEiJ_G0021924	protein coding gene	Chr16:19317782-19324540 (-)
CBA/J	MGP_CBAJ_G0022366	protein coding gene	Chr16:20619738-20627723 (-)
DBA/2J	MGP_DBA2J_G0022498	protein coding gene	Chr16:18443717-18450728 (-)
FVB/NJ	MGP_FVBNJ_G0022473	protein coding gene	Chr16:18413496-18426689 (-)
LP/J	MGP_LPJ_G0022565	protein coding gene	Chr16:19143910-19150991 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022493	protein coding gene	Chr16:20220416-20229183 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023091	protein coding gene	Chr16:19173912-19183114 (-)
PWK/PhJ	MGP_PWKPhJ_G0021664	protein coding gene	Chr16:18678038-18684912 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021494	protein coding gene	Chr16:18958616-18965401 (-)
WSB/EiJ	MGP_WSBEiJ_G0021967	protein coding gene	Chr16:19143568-19150367 (-)

Human Ortholog

TMEM41A, transmembrane protein 41A

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TMEM41A, transmembrane protein 41A
Synonyms

2900010K02Rik
Links

HGNC:30544

NCBI Gene ID: 90407

neXtProt AC: NX_Q96HV5

UniProt: Q96HV5
Chr Location

3q27.2; chr3:185476496-185499057 (-) GRCh38

MGI Vertebrate Homology

Tmem41a stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: TMEM41A
Gene Tree

Tmem41a

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
6 phenotype references

All Mutations and Alleles

9
Endonuclease-mediated

2
Gene trapped

6
Targeted

1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

13 strains or lines available

Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

27
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase tmem41a

ZFIN tmem41aa

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All Sequences

39
RefSeq

3
UniProt

3
CCDS

CCDS28064.1

Ensembl

ENSMUSG00000022856 (Evidence)
NCBI Gene

66664

			Length	Strain/Species	Flank
genomic	66664	NCBI Gene Model \| MGI Sequence Detail	13226	C57BL/6J	± kb
transcript	NM_025693	RefSeq \| MGI Sequence Detail	1359	C57BL/6
polypeptide	Q9D8U2	UniProt \| EBI \| MGI Sequence Detail	264	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000032513 transmembrane protein 41A

(term hierarchy)
InterPro Domains

IPR045014 Transmembrane protein 41A/B

IPR032816 VTT domain

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All nucleic 27

cDNA 27

Microarray probesets 3

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MGI:1920138

Summaries

All 26

Developmental Gene Expression 1

Gene Ontology 1

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Tmem41a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr140442	Chr16:21766286-21766327 (-)	-5 bp
Tssr140441	Chr16:21766203-21766267 (-)	67 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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