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Asb17 Gene Detail
Summary
  • Symbol
    Asb17
  • Name
    ankyrin repeat and SOCS box-containing 17
  • Synonyms
    4933436O18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914022
    NCBI Gene: 66772
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:153549884-153559252 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 78.68 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    422 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914022
 protein coding gene Chr3:153549846-153560719 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027997
 protein coding gene Chr3:157804547-157815241 (+)
A/J MGP_AJ_G0027956
 protein coding gene Chr3:152060894-152071760 (+)
AKR/J MGP_AKRJ_G0027922
 protein coding gene Chr3:156132285-156143573 (+)
BALB/cJ MGP_BALBcJ_G0027968
 protein coding gene Chr3:151869665-151880532 (+)
C3H/HeJ MGP_C3HHeJ_G0027698
 protein coding gene Chr3:156497673-156508586 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028411
 protein coding gene Chr3:162943495-162954589 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025749
 protein coding gene Chr3:146838074-146849265 (+)
CAST/EiJ MGP_CASTEiJ_G0027151
 protein coding gene Chr3:156606799-156617433 (+)
CBA/J MGP_CBAJ_G0027673
 protein coding gene Chr3:168825162-168836076 (+)
DBA/2J MGP_DBA2J_G0027813
 protein coding gene Chr3:151142267-151153337 (+)
FVB/NJ MGP_FVBNJ_G0027780
 protein coding gene Chr3:148514821-148525828 (+)
LP/J MGP_LPJ_G0027924
 protein coding gene Chr3:159133431-159144125 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027813
 protein coding gene Chr3:177294501-177306298 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028470
 protein coding gene Chr3:155766849-155777717 (+)
PWK/PhJ MGP_PWKPhJ_G0026874
 protein coding gene Chr3:151058320-151069092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026702
 protein coding gene Chr3:153931156-153941834 (+)
WSB/EiJ MGP_WSBEiJ_G0027231
 protein coding gene Chr3:156753211-156764284 (+)



Homology
more
  • Human Ortholog
    ASB17, ankyrin repeat and SOCS box containing 17
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASB17, ankyrin repeat and SOCS box containing 17
  • Synonyms
    Asb-17
  • Links
    NCBI Gene ID: 127247
    neXtProt AC: NX_Q8WXJ9
    UniProt: Q8WXJ9

  • Chr Location
    1p31.1; chr1:75918873-75932404 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a knock-out allele are fertile but exhibit oligozoospermia, abnormal ectoplasmic specialization morphology, and spermiation failure.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66772 NCBI Gene Model | MGI Sequence Detail 9369 C57BL/6J ±  kb
    transcript NM_025758 RefSeq | MGI Sequence Detail 1048 C57BL/6  
    polypeptide Q8VHP9 UniProt | EBI | MGI Sequence Detail 295 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 2
    References
    more
    • Summaries
      All 25
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory