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Krt20 Gene Detail
Summary
  • Symbol
    Krt20
  • Name
    keratin 20
  • Synonyms
    9030623C06Rik, CK20, cytokeratin 20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914059
    NCBI Gene: 66809
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99319229-99328976 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 62.92 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    418 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914059
protein coding gene Chr11:99319211-99328979 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019093
protein coding gene Chr11:102095355-102105038 (-)
A/J MGP_AJ_G0019061
protein coding gene Chr11:97795938-97806274 (-)
AKR/J MGP_AKRJ_G0019031
protein coding gene Chr11:100831972-100841719 (-)
BALB/cJ MGP_BALBcJ_G0019035
protein coding gene Chr11:98306198-98315925 (-)
C3H/HeJ MGP_C3HHeJ_G0018848
protein coding gene Chr11:100981811-100991513 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0017118
protein coding gene Chr11:95359486-95369602 (-)
CAST/EiJ MGP_CASTEiJ_G0018403
protein coding gene Chr11:101980344-101990132 (-)
CBA/J MGP_CBAJ_G0018819
protein coding gene Chr11:109618606-109628333 (-)
DBA/2J MGP_DBA2J_G0018927
protein coding gene Chr11:97363024-97372708 (-)
FVB/NJ MGP_FVBNJ_G0018916
protein coding gene Chr11:96873482-96883167 (-)
LP/J MGP_LPJ_G0018997
protein coding gene Chr11:102561136-102570823 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018943
protein coding gene Chr11:109289125-109298812 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019526
protein coding gene Chr11:101196330-101207429 (-)
PWK/PhJ MGP_PWKPhJ_G0018174
protein coding gene Chr11:98436727-98446701 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017962
protein coding gene Chr11:100947443-100956365 (-)
WSB/EiJ MGP_WSBEiJ_G0018451
protein coding gene Chr11:101165917-101175656 (-)



Homology
more
  • Human Ortholog
    KRT20, keratin 20
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT20, keratin 20
  • Synonyms
    CD20, CK-20, CK20, K20, KRT21
  • Links
    NCBI Gene ID: 54474
    neXtProt AC: NX_P35900
    UniProt: P35900

  • Chr Location
    17q21.2; chr17:40875889-40885242 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035775 Ensembl Gene Model | MGI Sequence Detail 9748 C57BL/6J ±  kb
transcript ENSMUST00000017743 Ensembl | MGI Sequence Detail 1927 Not Applicable  
polypeptide ENSMUSP00000017743 Ensembl | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 69
    Developmental Gene Expression 32
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:350794 Liu CY, et al., Wound-healing plasticity enables clonal expansion of founder progenitor cells in colitis. Dev Cell. 2023 Nov 6;58(21):2309-2325.e7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory