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Thap2 Gene Detail
Summary
  • Symbol
    Thap2
  • Name
    THAP domain containing, apoptosis associated protein 2
  • Synonyms
    2900040O07Rik, 9030625G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914066
    NCBI Gene: 66816
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:115204303-115220340 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 63.51 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    528 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914066
 protein coding gene Chr10:115204303-115220348 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017737
 protein coding gene Chr10:118073417-118089012 (-)
A/J MGP_AJ_G0017713
 protein coding gene Chr10:113542266-113557049 (-)
AKR/J MGP_AKRJ_G0017675
 protein coding gene Chr10:116838065-116852462 (-)
BALB/cJ MGP_BALBcJ_G0017676
 protein coding gene Chr10:113940137-113955051 (-)
C3H/HeJ MGP_C3HHeJ_G0017501
 protein coding gene Chr10:117061919-117077519 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018133
 protein coding gene Chr10:122180214-122195686 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015813
 protein coding gene Chr10:108169649-108184335 (-)
CAST/EiJ MGP_CASTEiJ_G0017063
 protein coding gene Chr10:117292086-117309789 (-)
CBA/J MGP_CBAJ_G0017470
 protein coding gene Chr10:126945077-126961179 (-)
DBA/2J MGP_DBA2J_G0017575
 protein coding gene Chr10:112695324-112709841 (-)
FVB/NJ MGP_FVBNJ_G0017570
 protein coding gene Chr10:111643186-111657359 (-)
LP/J MGP_LPJ_G0017650
 protein coding gene Chr10:118661168-118675868 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017599
 protein coding gene Chr10:129892272-129906648 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018171
 protein coding gene Chr10:116872281-116887572 (-)
PWK/PhJ MGP_PWKPhJ_G0016845
 protein coding gene Chr10:112760824-112778362 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016635
 protein coding gene Chr10:115675953-115692622 (-)
WSB/EiJ MGP_WSBEiJ_G0017123
 protein coding gene Chr10:117049310-117064883 (-)



Homology
more
  • Human Ortholog
    THAP2, THAP domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THAP2, THAP domain containing 2
  • Links
    NCBI Gene ID: 83591
    neXtProt AC: NX_Q9H0W7
    UniProt: Q9H0W7

  • Chr Location
    12q21.1; chr12:71664301-71680644 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66816 NCBI Gene Model | MGI Sequence Detail 16038 C57BL/6J ±  kb
transcript NM_025780 RefSeq | MGI Sequence Detail 4982 C57BL/6  
polypeptide Q9D305 UniProt | EBI | MGI Sequence Detail 217 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 6
Other
Accession IDs
less
MGI:1920176, MGI:2143609, MGI:2143661
References
more
  • Summaries
    All 36
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory