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Dolpp1 Gene Detail
Summary
  • Symbol
    Dolpp1
  • Name
    dolichyl pyrophosphate phosphatase 1
  • Synonyms
    0610011H20Rik, LSFR2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914093
    NCBI Gene: 57170
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30282266-30290541 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 21.68 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    210 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914093
 protein coding gene Chr2:30282261-30290541 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025567
 protein coding gene Chr2:28617245-28625491 (+)
A/J MGP_AJ_G0025545
 protein coding gene Chr2:27478139-27486414 (+)
AKR/J MGP_AKRJ_G0025514
 protein coding gene Chr2:28412399-28420674 (+)
BALB/cJ MGP_BALBcJ_G0025541
 protein coding gene Chr2:27605052-27613294 (+)
C3H/HeJ MGP_C3HHeJ_G0025302
 protein coding gene Chr2:28343294-28351536 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025986
 protein coding gene Chr2:29558284-29566559 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023394
 protein coding gene Chr2:26255202-26263420 (+)
CAST/EiJ MGP_CASTEiJ_G0024764
 protein coding gene Chr2:28242617-28250891 (+)
CBA/J MGP_CBAJ_G0025279
 protein coding gene Chr2:30562107-30570349 (+)
DBA/2J MGP_DBA2J_G0025412
 protein coding gene Chr2:27267554-27275829 (+)
FVB/NJ MGP_FVBNJ_G0025375
 protein coding gene Chr2:27087571-27095846 (+)
LP/J MGP_LPJ_G0025498
 protein coding gene Chr2:28525985-28534227 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025405
 protein coding gene Chr2:30445178-30453453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026044
 protein coding gene Chr2:28327049-28335291 (+)
PWK/PhJ MGP_PWKPhJ_G0024511
 protein coding gene Chr2:27107916-27116167 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024311
 protein coding gene Chr2:28446243-28454440 (+)
WSB/EiJ MGP_WSBEiJ_G0024832
 protein coding gene Chr2:28457762-28466039 (+)



Homology
more
  • Human Ortholog
    DOLPP1, dolichyldiphosphatase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DOLPP1, dolichyldiphosphatase 1
  • Synonyms
    LSFR2
  • Links
    NCBI Gene ID: 57171
    neXtProt AC: NX_Q86YN1
    UniProt: Q86YN1

  • Chr Location
    9q34.11; chr9:129081111-129090438 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    70
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026856 Ensembl Gene Model | MGI Sequence Detail 8276 C57BL/6J ±  kb
transcript ENSMUST00000028209 Ensembl | MGI Sequence Detail 2251 Not Applicable  
polypeptide ENSMUSP00000028209 Ensembl | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 3
Other
Accession IDs
less
MGI:1927574
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory