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Riok3 Gene Detail
Summary
  • Symbol
    Riok3
  • Name
    RIO kinase 3
  • Synonyms
    1200013N13Rik, D18Ertd331e, E130306C24Rik, Sudd
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914128
    NCBI Gene: 66878
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:12261798-12290444 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 6.15 cM, cytoband A2
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    955 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914128
 protein coding gene Chr18:12259114-12290444 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024156
 protein coding gene Chr18:9278688-9309523 (+)
A/J MGP_AJ_G0024118
 protein coding gene Chr18:9133114-9162032 (+)
AKR/J MGP_AKRJ_G0024085
 protein coding gene Chr18:9399874-9441857 (+)
BALB/cJ MGP_BALBcJ_G0024117
 protein coding gene Chr18:9074403-9103003 (+)
C3H/HeJ MGP_C3HHeJ_G0023884
 protein coding gene Chr18:9284066-9313078 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024562
 protein coding gene Chr18:9766864-9795386 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022001
 protein coding gene Chr18:8714625-8742035 (+)
CAST/EiJ MGP_CASTEiJ_G0023361
 protein coding gene Chr18:9159103-9187218 (+)
CBA/J MGP_CBAJ_G0023856
 protein coding gene Chr18:9890921-9919537 (+)
DBA/2J MGP_DBA2J_G0023985
 protein coding gene Chr18:8979453-9009205 (+)
FVB/NJ MGP_FVBNJ_G0023950
 protein coding gene Chr18:8840015-8868175 (+)
LP/J MGP_LPJ_G0024068
 protein coding gene Chr18:9381982-9409945 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023979
 protein coding gene Chr18:10068853-10097859 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024608
 protein coding gene Chr18:9170372-9200772 (+)
PWK/PhJ MGP_PWKPhJ_G0023107
 protein coding gene Chr18:9040212-9068629 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022916
 protein coding gene Chr18:9437161-9472112 (+)
WSB/EiJ MGP_WSBEiJ_G0023427
 protein coding gene Chr18:9173028-9201265 (+)



Homology
more
  • Human Ortholog
    RIOK3, RIO kinase 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIOK3, RIO kinase 3
  • Synonyms
    SUDD
  • Links
    NCBI Gene ID: 8780
    neXtProt AC: NX_O14730
    UniProt: O14730

  • Chr Location
    18q11.2; chr18:23453287-23486603 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    54
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    13
  • cDNA Data
    137
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024404 Ensembl Gene Model | MGI Sequence Detail 28647 C57BL/6J ±  kb
    transcript ENSMUST00000025270 Ensembl | MGI Sequence Detail 3790 Not Applicable  
    polypeptide ENSMUSP00000025270 Ensembl | MGI Sequence Detail 519 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 141
      cDNA 139
      Primer pair 2

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1196296, MGI:2445149
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory