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Ndufb7 Gene Detail
Summary
  • Symbol
    Ndufb7
  • Name
    NADH:ubiquinone oxidoreductase subunit B7
  • Synonyms
    1110002H15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914166
    NCBI Gene: 66916
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:84293387-84298252 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 40.22 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914166
 protein coding gene Chr8:84293300-84298255 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033833
 protein coding gene Chr8:84387455-84393772 (+)
A/J MGP_AJ_G0033816
 protein coding gene Chr8:81094724-81099610 (+)
AKR/J MGP_AKRJ_G0033742
 protein coding gene Chr8:83490468-83495414 (+)
BALB/cJ MGP_BALBcJ_G0033809
 protein coding gene Chr8:81198274-81203252 (+)
C3H/HeJ MGP_C3HHeJ_G0033519
 protein coding gene Chr8:84105742-84112077 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034329
 protein coding gene Chr8:87620403-87625361 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031271
 protein coding gene Chr8:74887930-74892950 (+)
CAST/EiJ MGP_CASTEiJ_G0032849
 protein coding gene Chr8:83504316-83509574 (+)
CBA/J MGP_CBAJ_G0033497
 protein coding gene Chr8:90768295-90773151 (+)
DBA/2J MGP_DBA2J_G0033650
 protein coding gene Chr8:80736213-80741398 (+)
FVB/NJ MGP_FVBNJ_G0033596
 protein coding gene Chr8:79651941-79657511 (+)
LP/J MGP_LPJ_G0033740
 protein coding gene Chr8:84507324-84514971 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033638
 protein coding gene Chr8:93263114-93270657 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034346
 protein coding gene Chr8:83468215-83473110 (+)
PWK/PhJ MGP_PWKPhJ_G0032553
 protein coding gene Chr8:79952726-79958500 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032390
 protein coding gene Chr8:82262830-82268100 (+)
WSB/EiJ MGP_WSBEiJ_G0032962
 protein coding gene Chr8:83865314-83871102 (+)



Homology
more
  • Human Ortholog
    NDUFB7, NADH:ubiquinone oxidoreductase subunit B7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFB7, NADH:ubiquinone oxidoreductase subunit B7
  • Synonyms
    B18, CI-B18, MC1DN39
  • Links
    NCBI Gene ID: 4713
    neXtProt AC: NX_P17568
    UniProt: P17568

  • Chr Location
    19p13.12; chr19:14566078-14572066 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NDUFB7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    38 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ndufb7
  • Incidental Mutations
    Mutagenetix
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    95
  • cDNA Data
    154
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66916 NCBI Gene Model | MGI Sequence Detail 4866 C57BL/6J ±  kb
transcript NM_025843 RefSeq | MGI Sequence Detail 533 C57BL/6  
polypeptide Q9CR61 UniProt | EBI | MGI Sequence Detail 137 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 155
    cDNA 154
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 70
    Developmental Gene Expression 4
    Gene Ontology 10
    Phenotypes 38
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:357794 Milenkovic D, et al., Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes. Cell Metab. 2023 Oct 3;35(10):1799-1813.e7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory