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Dsn1 Gene Detail
Summary
  • Symbol
    Dsn1
  • Name
    DSN1 homolog, MIS12 kinetochore complex component
  • Synonyms
    1700022L09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914184
    NCBI Gene: 66934
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:156837185-156849074 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.89 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    295 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914184
 protein coding gene Chr2:156836982-156849074 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026773
 protein coding gene Chr2:161964538-161977132 (-)
A/J MGP_AJ_G0026739
 protein coding gene Chr2:155494508-155506561 (-)
AKR/J MGP_AKRJ_G0026710
 protein coding gene Chr2:160059042-160071084 (-)
BALB/cJ MGP_BALBcJ_G0026748
 protein coding gene Chr2:155777868-155789744 (-)
C3H/HeJ MGP_C3HHeJ_G0026490
 protein coding gene Chr2:160367020-160379038 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027197
 protein coding gene Chr2:166731658-166750057 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024567
 protein coding gene Chr2:148944676-148957654 (-)
CAST/EiJ MGP_CASTEiJ_G0025952
 protein coding gene Chr2:160707880-160719931 (-)
CBA/J MGP_CBAJ_G0026467
 protein coding gene Chr2:172784819-172795649 (-)
DBA/2J MGP_DBA2J_G0026605
 protein coding gene Chr2:154664332-154676377 (-)
FVB/NJ MGP_FVBNJ_G0026572
 protein coding gene Chr2:153055353-153067837 (-)
LP/J MGP_LPJ_G0026710
 protein coding gene Chr2:162060064-162072553 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026593
 protein coding gene Chr2:176631594-176645070 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027253
 protein coding gene Chr2:159884289-159895053 (-)
PWK/PhJ MGP_PWKPhJ_G0025686
 protein coding gene Chr2:154172905-154185090 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025489
 protein coding gene Chr2:158822680-158838987 (-)
WSB/EiJ MGP_WSBEiJ_G0026022
 protein coding gene Chr2:160764328-160778955 (-)



Homology
more
  • Human Ortholog
    DSN1, DSN1 component of MIS12 kinetochore complex
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DSN1, DSN1 component of MIS12 kinetochore complex
  • Synonyms
    C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13
  • Links
    NCBI Gene ID: 79980
    neXtProt AC: NX_Q9H410
    UniProt: Q9H410

  • Chr Location
    20q11.23; chr20:36751791-36773818 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    10
  • cDNA Data
    62
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027635 Ensembl Gene Model | MGI Sequence Detail 11890 C57BL/6J ±  kb
transcript ENSMUST00000103130 Ensembl | MGI Sequence Detail 2636 Not Applicable  
polypeptide ENSMUSP00000099419 Ensembl | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 64
    cDNA 64

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139390
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory