About   Help   FAQ
Zcchc18 Gene Detail
Summary
  • Symbol
    Zcchc18
  • Name
    zinc finger, CCHC domain containing 18
  • Synonyms
    1500031H04Rik, Sizn2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914245
    NCBI Gene: 66995
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:135893904-135899221 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 59.10 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    173 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914245
 protein coding gene ChrX:135893128-135899221 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036112
 protein coding gene ChrX:134407338-134412871 (+)
A/J MGP_AJ_G0036091
 protein coding gene ChrX:133819623-133825106 (+)
AKR/J MGP_AKRJ_G0036015
 protein coding gene ChrX:138107391-138112708 (+)
BALB/cJ MGP_BALBcJ_G0036080
 protein coding gene ChrX:132231341-132236641 (+)
C3H/HeJ MGP_C3HHeJ_G0035789
 protein coding gene ChrX:134496075-134501953 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036605
 protein coding gene ChrX:138340084-138346421 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033430
 protein coding gene ChrX:125743400-125748645 (+)
CAST/EiJ MGP_CASTEiJ_G0035079
 protein coding gene ChrX:115244442-115249754 (+)
CBA/J MGP_CBAJ_G0035765
 protein coding gene ChrX:142584630-142589953 (+)
DBA/2J MGP_DBA2J_G0035922
 protein coding gene ChrX:133110215-133115525 (+)
FVB/NJ MGP_FVBNJ_G0035857
 protein coding gene ChrX:132319020-132324922 (+)
LP/J MGP_LPJ_G0036015
 protein coding gene ChrX:135412010-135417912 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035893
 protein coding gene ChrX:149884390-149890193 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036641
 protein coding gene ChrX:133786975-133792284 (+)
PWK/PhJ MGP_PWKPhJ_G0034772
 protein coding gene ChrX:112262404-112267727 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034599
 protein coding gene ChrX:115847243-115852544 (+)
WSB/EiJ MGP_WSBEiJ_G0035214
 protein coding gene ChrX:132119071-132124373 (+)



Homology
more
  • Human Ortholog
    ZCCHC18, zinc finger CCHC-type containing 18
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZCCHC18, zinc finger CCHC-type containing 18
  • Synonyms
    PNMA7B, SIZN2
  • Links
    NCBI Gene ID: 644353
    neXtProt AC: NX_P0CG32
    UniProt: P0CG32

  • Chr Location
    Xq22.2; chrX:104112131-104115842 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1117
  • Tissues
    63
  • cDNA Data
    56
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031428 Ensembl Gene Model | MGI Sequence Detail 5318 C57BL/6J ±  kb
transcript ENSMUST00000113067 Ensembl | MGI Sequence Detail 2259 Not Applicable  
polypeptide ENSMUSP00000108690 Ensembl | MGI Sequence Detail 393 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 56
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 27
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:333987 Bohuslavova R, et al., ISL1 controls pancreatic alpha cell fate and beta cell maturation. Cell Biosci. 2023 Mar 10;13(1):53
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory