Rpp14 MGI Mouse Gene Detail - MGI:1914303 - ribonuclease P 14 subunit

Symbol

Rpp14
Name

ribonuclease P 14 subunit
Synonyms

2610511E03Rik

Feature Type

protein coding gene
IDs

MGI:1914303
NCBI Gene: 67053
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr14:14377939-14389406 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 4.70 cM
Mapping Data

2 experiments

SNPs within 2kb

555 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914303	protein coding gene	Chr14:14377927-14389460 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020987	protein coding gene	Chr14:413349-424633 (+)
A/J	MGP_AJ_G0020935	protein coding gene	Chr14:391628-402938 (+)
AKR/J	MGP_AKRJ_G0020912	protein coding gene	Chr14:393078-404411 (+)
BALB/cJ	MGP_BALBcJ_G0020937	protein coding gene	Chr14:386921-398559 (+)
C3H/HeJ	MGP_C3HHeJ_G0020722	protein coding gene	Chr14:395810-407958 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021371	protein coding gene	Chr14:426975-438496 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018940	protein coding gene	Chr14:1313300-1324625 (+)
CAST/EiJ	MGP_CASTEiJ_G0020244	protein coding gene	Chr14:393357-404437 (+)
CBA/J	MGP_CBAJ_G0020688	protein coding gene	Chr14:429974-445211 (+)
DBA/2J	MGP_DBA2J_G0020811	protein coding gene	Chr14:368974-389441 (+)
FVB/NJ	MGP_FVBNJ_G0020793	protein coding gene	Chr14:370978-382244 (+)
LP/J	MGP_LPJ_G0020888	protein coding gene	Chr14:390135-401416 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020819	protein coding gene	Chr14:423625-434790 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021404	protein coding gene	Chr14:396670-409400 (+)
PWK/PhJ	MGP_PWKPhJ_G0019996	protein coding gene	Chr14:395526-406936 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019817	protein coding gene	Chr14:399852-414527 (+)
WSB/EiJ	MGP_WSBEiJ_G0020302	protein coding gene	Chr14:393334-406070 (+)

Human Ortholog

RPP14, ribonuclease P/MRP subunit p14

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPP14, ribonuclease P/MRP subunit p14
Synonyms

P14
Links

HGNC:30327

NCBI Gene ID: 11102

neXtProt AC: NX_O95059

UniProt: O95059
Chr Location

3p14.3; chr3:58306245-58324695 (+) GRCh38

MGI Vertebrate Homology

Rpp14 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPP14
Gene Tree

Rpp14

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Phenotype Summary

3 phenotype references

All Mutations and Alleles

3
Endonuclease-mediated

1
Targeted

2
Find Mice (IMSR)

32 strains or lines available

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All GO Annotations

14
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

801
Tissues

95
cDNA Data

12
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpp14

ZFIN rpp14

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All Sequences

43
RefSeq

2
UniProt

1
CCDS

CCDS26809.1

Ensembl

ENSMUSG00000023156 (Evidence)
NCBI Gene

67053

			Length	Strain/Species	Flank
genomic	ENSMUSG00000023156	Ensembl Gene Model \| MGI Sequence Detail	11468	C57BL/6J	± kb
transcript	ENSMUST00000180369	Ensembl \| MGI Sequence Detail	477	Not Applicable
polypeptide	ENSMUSP00000136494	Ensembl \| MGI Sequence Detail	158	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000036940 hydroxyacyl-thioester dehydratase type 2, mitochondrial

(term hierarchy)

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All nucleic 13

cDNA 12

Primer pair 1

Microarray probesets 6

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MGI:2145580

Summaries

All 25

Developmental Gene Expression 2

Gene Ontology 3

Phenotypes 3
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Rpp14:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr124233	Chr14:14389374-14389387 (-)	25 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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